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Emotional Consequences of Finasteride: Fool's Gold.
Christine Anne Ganzer1, Alan Roy Jacobs1
11 Hunter-Bellevue School of Nursing, New York, NY, USA.
American Journal of Men'S Health
|February 13, 2016
Summary
Finasteride users often experience depression and anxiety, with nearly 50% showing clinically significant depression. Preexisting psychiatric history may influence these outcomes, highlighting the need for careful patient screening and counseling regarding finasteride
Area of Science:
- Dermatology
- Psychiatry
- Pharmacology
Background:
- Androgenetic alopecia causes hair loss and psychological distress.
- Finasteride, a dihydrotestosterone inhibitor, treats hair loss but can cause adverse effects (post-finasteride syndrome).
- Limited research explores psychological impacts of finasteride, especially concerning pre-existing mental health conditions.
Purpose of the Study:
- To investigate the influence of personal/familial psychiatric history and personality traits on anxiety and depression in finasteride users.
- To assess the prevalence of psychiatric diagnoses and mental health conditions within this patient group.
Main Methods:
- Online survey distributed to finasteride users.
- Utilized Beck Depression Inventory (BDI) and Beck Anxiety Inventory (BAI) for symptom assessment.
- Employed Ten-Item Personality Inventory (TIPI) to evaluate personality traits.
Main Results:
- Almost 57% of participants reported a personal psychiatric diagnosis.
- 28% had a first-degree relative with a mental health disorder.
- Nearly 50% reported clinically significant depression (BDI scores), and 34% experienced anxiety (BAI scores).
- No statistically significant trends were found regarding personality traits.
Conclusions:
- Finasteride users exhibit high rates of depression and anxiety.
- A significant proportion of users have a personal or familial psychiatric history.
- Clinicians should screen for psychiatric history and counsel patients on potential psychological risks of finasteride, weighing the risk/benefit ratio.
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