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Updated: Mar 25, 2026

Co-analysis of Brain Structure and Function using fMRI and Diffusion-weighted Imaging
Published on: November 8, 2012
The Interface between Neuroscience and Neuro-Psychoanalysis: Focus on Brain Connectivity
Anatolia Salone1, Alessandra Di Giacinto1, Carlo Lai2
1Department of Neuroscience, Imaging and Clinical Sciences and Institute for Advanced Biomedical Technologies-ITAB, University G. d'AnnunzioChieti-Pescara, Italy; Institute of Psychiatry, University G. d'AnnunzioChieti-Pescara, Italy.
Neuroscience and psychoanalysis, particularly brain connectivity research, offer new insights into schizophrenia. Understanding networks like the default mode network (DMN) may explain core psychopathological features.
Area of Science:
- Neuroscience
- Psychoanalysis
- Psychiatry
Background:
- Traditional neuroscience approaches to psychiatric disorders are limited.
- Psychoanalysis and neuroscience can offer a complementary understanding of the mind.
- Advances in brain connectivity research bridge these fields.
Purpose of the Study:
- To explore the impact of brain connectivity knowledge on neuropsychoanalysis.
- To focus on schizophrenia as a case study for this integration.
- To link neural correlates with psychodynamic concepts in schizophrenia.
Main Methods:
- Review of brain connectivity studies in schizophrenia.
- Analysis of alterations in brain circuitry, focusing on cortical midline structures (CMS) and the default mode network (DMN).
- Connecting neuroscientific findings with psychodynamic theories.
Main Results:
- Schizophrenia exhibits complex alterations in brain functioning and circuitry.
- The default mode network (DMN) and cortical midline structures (CMS) are implicated.
- These networks may underlie ego disturbances and impaired primary process thinking.
Conclusions:
- Brain connectivity research supports the integration of neuroscience and psychoanalysis.
- Neuropsychoanalysis offers a framework for understanding schizophrenia's psychopathology.
- This integrated approach enhances our comprehension of higher brain functions and mental disorders.
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