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Transient gall bladder dilatation associated with hypokalaemia in a patient with Bartter syndrome

A Goren1, R Drachman, I Hadas-Halperin

  • 1Division of Paediatric Nephrology, Shaare Zedek Medical Centre, Jerusalem, Israel.

European Journal of Pediatrics
|November 1, 1989
PubMed

Insights

Bartter syndrome, a kidney disorder, can cause hypokalemia and gallbladder enlargement in infants. Treatment with potassium and indomethacin normalized potassium levels and resolved gallbladder issues.

Area of Science:

  • Pediatric Nephrology
  • Clinical Medicine

Background:

  • Bartter syndrome is a rare genetic disorder affecting kidney tubules.
  • It leads to electrolyte imbalances, including hypokalemia (low potassium).
  • Hypokalemia can manifest with various clinical symptoms, including neuromuscular disturbances.

Observation:

  • A 5.5-month-old infant presented with hypokalemia and gallbladder dilatation.
  • The infant was diagnosed with Bartter syndrome.
  • A right-sided abdominal mass was noted, potentially related to gallbladder enlargement.

Findings:

  • Oral potassium supplementation and indomethacin treatment were initiated.
  • Serum potassium levels normalized to the low-normal range.
  • Gallbladder enlargement resolved following treatment.

Implications:

  • Bartter syndrome should be considered in the differential diagnosis of hypokalemic infants.
  • Gallbladder dilatation can be a presenting sign of Bartter syndrome-induced hypokalemia.
  • Early diagnosis and management are crucial for favorable outcomes in pediatric Bartter syndrome.

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