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Updated: Mar 25, 2026

Preparation of Stable Bicyclic Aziridinium Ions and Their Ring-Opening for the Synthesis of Azaheterocycles
Published on: August 22, 2018
Crystal structure of (±)-(5SR,6SR)-6-ethenyl-1-[(RS)-1-phenyl-eth-oxy]-1-aza-spiro-[4.5]decan-2-one
Takeshi Oishi1, Shio Yamamoto2, Takashi Yokoyama2
1School of Medicine, Keio University, Hiyoshi 4-1-1, Kohoku-ku, Yokohama 223-8521, Japan.
Abstract:
In the title compound, C19H25NO2, the pyrrolidine ring adopts an envelope form, with the spiro C atom as the flap, while the cyclo-hexane ring shows a chair form. A weak intra-molecular C-H⋯O inter-action supports the mol-ecular conformation, generating an S(6) ring motif. In the crystal, pairs of C-H⋯O inter-actions connect the mol-ecules into inversion dimers with an R 2 (2)(16) ring motif. The dimers are linked by a second pair of C-H⋯O inter-actions, enclosing an R 4 (2)(12) ring motif, into a tape structure along the b axis.
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