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Genetic Variation in NFKBIE Is Associated With Increased Risk of Pneumococcal Meningitis in Children

Lene F Lundbo1, Zitta Barrella Harboe2, Louise N Clausen3

  • 1Department of Infectious Diseases, Hvidovre Hospital, University of Copenhagen, Hvidovre, Denmark; Clinical Research Centre, Hvidovre Hospital, University of Copenhagen, Hvidovre, Denmark; Faculty of Health Sciences, University of Copenhagen, Copenhagen, Denmark.

Ebiomedicine
|February 13, 2016
PubMed
Abstract

Keywords:
CI, confidence intervalsCRS, Danish Civil Registration SystemCSF, cerebrospinal fluidDNPR, Danish National Patient RegistryDNSB, Danish Neonatal Screening BiobankHWE, Hardy–Weinberg equilibriumIMD, invasive meningococcal diseaseIPD, Invasive pneumococcal diseaseIQR, interquartile rangeInvasive Meningococcal DiseaseInvasive Pneumococcal DiseaseLD, linkage disequilibriumNF, nuclear factor-κBNuclear Factor-κBOR, odds ratioPneumoccoccal SerotypesRSV, respiratory syncytial virusSNPs, single nucleotide polymorphismsSSI, Statens Serum InstitutWGA, whole-genome-amplificationaOR, adjusted odds ratio

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