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Related Experiment Videos

Clinical experience with ioversol for angiography.

M A Bettmann1

  • 1Department of Radiology, Boston University School of Medicine, Massachusetts.

Investigative Radiology
|June 1, 1989
PubMed
Summary

Ioversol, a new nonionic, low-osmolality contrast agent, demonstrates safety and diagnostic efficacy in over 500 patients for various intra-arterial angiography procedures. This agent shows promise as a valuable addition to existing low-osmolality contrast options.

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Area of Science:

  • Radiology
  • Medical Imaging
  • Pharmacology

Background:

  • Ioversol is a novel nonionic, low-osmolality contrast agent.
  • Its chemical properties and basic toxicity have been established.
  • Previous clinical studies have reviewed its use.

Purpose of the Study:

  • To review worldwide experience with the intra-arterial use of ioversol.
  • To assess the safety and diagnostic efficacy of ioversol in clinical practice.

Main Methods:

  • Review of worldwide clinical data on ioversol use.
  • Analysis of 23 monitored studies involving over 500 patients.
  • Comparison with high- and low-osmolality contrast agents.

Main Results:

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  • Ioversol was administered to over 500 patients for various intra-arterial angiographies.
  • 23 studies confirmed ioversol's safety and diagnostic efficacy.
  • No deaths or severe reactions were reported with ioversol use.

Conclusions:

  • Ioversol is safe and effective for intra-arterial angiography.
  • It offers a valuable alternative to existing low-osmolality contrast agents.
  • Further use of ioversol is anticipated in clinical settings.