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Updated: Aug 11, 2026
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In vitro tRNA Methylation Assay with the Entamoeba histolytica DNA and tRNA Methyltransferase Dnmt2 (Ehmeth) Enzyme
Published on: October 19, 2010
[Serum methotrexate determination by microbiological assay in patients receiving high-dosage methotrexate (author's
Wiener Klinische Wochenschrift
|July 15, 1977
Abstract:
Microbiological assay according to Burchenal (modified by Mehta) is used for the determination of the serum methotrexate (MTX) level. Fifty cycles of high-dose MTX therapy were monitored in 11 patients with osteogenic sarcoma. The results showed close correlation with the clinical course of the therapy. The serum level of MTX was elevated in patients with symptoms of toxicity.
