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Updated: Mar 25, 2026
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Published on: November 8, 2018
Cerebral Microdialysis
Bethany Young1, Atul Kalanuria2, Monisha Kumar3
1Department of Nursing, Hospital of the University of Pennsylvania, 3400 Spruce Street, 2nd Floor Rhoads Building, Philadelphia, PA 19104, USA.
Abstract:
A variety of neuromonitoring techniques are available to aid in the care of neurocritically ill patients. However, traditional monitors lack the ability to measure brain biochemistry and may provide inadequate warning of potentially reversible deleterious conditions. Cerebral microdialysis (CMD) is a safe, novel method of monitoring regional brain biochemistry. Analysis of CMD analytes as part of a multimodal approach may help inform clinical decision making, guide medical treatments, and aid in prognostication of patient outcome. Its use is most frequently documented in traumatic brain injury and subarachnoid hemorrhage. Incorporating CMD into clinical practice is a multidisciplinary effort.
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