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Updated: Mar 25, 2026

Esophageal Heat Transfer for Patient Temperature Control and Targeted Temperature Management
Published on: November 21, 2017
Targeted Temperature Modulation in the Neuroscience Patient
Marie Wilson1, Amy Della Penna1
1Neuroscience Intensive Care Unit, Thomas Jefferson University Hospital, 111 South 11th Street, Gibbon Building, Room 9300, Philadelphia, PA 19107, USA.
Abstract:
There are many approaches to and opportunities for implementing temperature modulation in critically ill patients, but barriers also exist. Conceptually, the process of cooling is rather straightforward; however, targeted temperature management is anything but simplistic. The need for a collaborative approach (physicians champions, nursing support, respiratory therapists, pharmacists, laboratory personnel, and supply chain representatives) to address definitions of normothermia and fever, patient inclusion/exclusion criteria for therapy based on underlying neurorelated pathologies, determination of methods of induction/maintenance, monitoring required, education planning, and strategies to minimize potential complications are warranted.
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