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Published on: January 7, 2019
Farmer's Lung Disease. A Review
Esteban Cano-Jiménez1, Adelaida Acuña1, María Isabel Botana1
1Grupo Gallego Multidisciplinar de Enfermedades Pulmonares Intersticiales Difusas (GAMEPID), Sociedad Gallega de Patología Respiratoria (SOGAPAR), España.
Farmer's lung disease (FLD), a type of hypersensitivity pneumonitis, is likely underdiagnosed in agricultural settings. Early diagnosis and antigen avoidance are crucial for managing this occupational lung disease.
Area of Science:
- Occupational Medicine
- Pulmonary Medicine
- Immunology
Background:
- Farmer's lung disease (FLD) is a hypersensitivity pneumonitis (HP) from inhaling agricultural microorganisms.
- High humidity in agricultural workplaces promotes the growth of causative agents like actinomycetes and fungi.
- FLD is likely underdiagnosed, particularly in regions like northern Spain with favorable climatic conditions.
Purpose of the Study:
- To highlight the underdiagnosis of Farmer's lung disease (FLD).
- To discuss the known epidemiology, clinical presentations, and diagnostic criteria for FLD.
- To emphasize the importance of antigen avoidance and preventive measures in managing FLD.
Main Methods:
- Review of existing literature on FLD epidemiology and clinical presentation.
- Analysis of diagnostic criteria including clinical, radiological, lung function, bronchoalveolar lavage, and serological findings.
- Evaluation of current treatment strategies, focusing on antigen avoidance and corticosteroid therapy.
Main Results:
- FLD presents in acute and chronic forms depending on antigen exposure concentration and duration.
- Diagnosis requires compatible clinical, radiological, and immunological findings, including lymphocytosis in bronchoalveolar lavage and antigen sensitivity.
- Antigen avoidance is the primary treatment; corticosteroids may aid acute form resolution but lack evidence for long-term efficacy or mortality reduction.
Conclusions:
- Farmer's lung disease is an underdiagnosed occupational illness requiring increased awareness and diagnostic efforts.
- Effective management hinges on patient education regarding preventive measures and antigen avoidance.
- Further controlled studies are needed to clarify the role of immunosuppressive and long-term corticosteroid therapies in FLD.
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