Related Experiment Video
Updated: Mar 25, 2026

An R-Based Landscape Validation of a Competing Risk Model
Published on: September 16, 2022
Bayesian reclassification statistics for assessing improvements in diagnostic accuracy
Zhipeng Huang1,2,3, Jialiang Li2,3,4, Ching-Yu Cheng3,4
1McDermott Center for Human Growth and Development, UT Southwestern Medical Center, Dallas, 75390, TX, U.S.A.
Abstract:
We propose a Bayesian approach to the estimation of the net reclassification improvement (NRI) and three versions of the integrated discrimination improvement (IDI) under the logistic regression model. Both NRI and IDI were proposed as numerical characterizations of accuracy improvement for diagnostic tests and were shown to retain certain practical advantage over analysis based on ROC curves and offer complementary information to the changes in area under the curve. Our development is a new contribution towards Bayesian solution for the estimation of NRI and IDI, which eases computational burden and increases flexibility. Our simulation results indicate that Bayesian estimation enjoys satisfactory performance comparable with frequentist estimation and achieves point estimation and credible interval construction simultaneously. We adopt the methodology to analyze a real data from the Singapore Malay Eye Study. Copyright © 2016 John Wiley & Sons, Ltd.
Related Concept Videos
Receiver Operating Characteristic Plot
Sensitivity, Specificity, and Predicted Value
Sensitivity is the...
Testing a Claim about Standard Deviation
The hypothesis testing for the claim of population standard deviation (or variance) requires the data and samples to be random and unbiased. The population distribution also must be normal. There is no specific requirement on the sample size as the estimation is based on the chi-square distribution.
As a first step, the hypothesis (null and alternative) concerning the claim about...
Accuracy and Errors in Hypothesis Testing
In hypothesis testing, the probability of making a Type I error, denoted as α, is commonly set at 0.05. This significance level indicates a 5%...
Types of Biopharmaceutical Studies: Controlled and Non-Controlled Approaches
Non-controlled studies, commonly employed for initial exploration, lack a control group, rendering them susceptible to biases and external influences. In contrast,...
Expected Frequencies in Goodness-of-Fit Tests

