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Frequency of Candida albicans in Patients with Funguria
Sana Jamil1, Naz Jamil1, Uzma Saad2
1Department of Microbiology, Sindh Institute of Urology and Transplantation, Karachi.
Objective:
To determine the frequency of Candida albicansin patients with funguria.
Study Design:
Descriptive cross-sectional study.
Place And Duration Of Study:
Department of Microbiology, Sindh Institute of Urology and Transplantation, from July to December 2012.
Methodology:
Patients’ urine samples with fungus/Candida were included. Candida albicans was identified by the production of tubular structures (germ tubes) on microscopy as per standard procedure followed by inoculation on Chrom agar (Oxoid) and Corn Meal-Tween 80 agar (Oxoid). The identification of other non-albicans Candidaspecies was also done both microscopically and macroscopically as per standard procedure.
Results:
Out of the 289 isolates, 204 (70.6%) were male patients and 85 (29.4%) were female patients, with 165 (57.1%) from the out-patients and 124 (42.9%) from the in-patients. Five species of Candidawere found to be prevalent including 87 (30.1%) Candida albicans, 176 (60.9%) Candida tropicalis, 14 (4.8%) Candida parapsilosis, 8 (2.8%) Candida glabrata and 4 (1.4%) Candida lusitaniae. Majority of patients with funguria were aged above 50 years (60.2%).
Conclusion:
In the present study, 30.1% patients with funguria had Candida albicans. The most frequently isolated species was Candida tropicalis(60.9%), followed by other non-albicansCandida. This study has shown the emergence of non-albicans Candidaas a major cause of candiduria.
