Psychophysiology as a core strategy in RDoC
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Updated: Mar 25, 2026

Psychophysiological Assessment of the Effectiveness of Emotion Regulation Strategies in Childhood
Published on: February 11, 2017
Gregory A Miller1, Brigitte S Rockstroh2, Holly K Hamilton1
1Department of Psychology & Department of Psychiatry and Biohavioral Sciences, University of California, Los Angeles, Los Angeles, California, USA.
Abstract:
The Research Domain Criteria (RDoC) initiative of the National Institute of Mental Health shows great promise in providing guidance for research on mental illness but has prompted considerable controversy. Papers by Yancey, Venables, and Patrick and Kozak and Cuthbert illustrate and clarify a number of important features of RDoC. The present commentary evaluates the former paper in light of the latter paper and addresses several common misunderstandings about RDoC. The concept of endophenotypes and diverse psychophysiological approaches will likely be central in RDoC-inspired research.
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