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Updated: Aug 10, 2026
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A Piglet Model of Neonatal Hypoxic-Ischemic Encephalopathy
Published on: May 16, 2015
Summary
Neonatal adrenal hemorrhage, detected via ultrasound, occurs frequently (28.7%). While often resolving without treatment, it is linked to neurological issues in over 30% of affected newborns.
Area of Science:
- Neonatal medicine
- Pediatric radiology
- Diagnostic imaging
Context:
- Neonatal adrenal hemorrhage diagnosis using ultrasound screening.
- High observed frequency (28.7%) compared to literature (1.7-6.0%).
- Ultrasound identified three types: cortical, medullar, and apoplectiform.
Purpose:
- To report the high incidence of neonatal adrenal hemorrhage detected by ultrasound.
- To analyze the clinical course, ultrasound findings, and risk factors.
- To correlate adrenal hemorrhage with neurological outcomes in neonates.
Summary:
- A six-month ultrasound screening of 870 neonates identified 25 cases of adrenal hemorrhage (28.7% incidence).
- Most hemorrhages resolved within 4 months without intervention or electrolyte disturbances.
- Over 30% of affected neonates exhibited pathological neurological symptoms or intracranial hemorrhage.
Impact:
- Highlights the high prevalence of neonatal adrenal hemorrhage detectable by ultrasound.
- Suggests a link between adrenal hemorrhage and adverse neurological outcomes in newborns.
- Identifies risk factors including large-for-date status, intrauterine asphyxia, and difficult deliveries.
