Idiopathic retroperitoneal fibrosis associated with Hashimoto's thyroiditis in a patient with a single functioning...

Area of Science:

• Nephrology
• Endocrinology
• Immunology

Background:

• Retroperitoneal fibrosis (RPF) is a rare fibroinflammatory condition affecting the retroperitoneum, often causing ureteral obstruction.
• Idiopathic RPF is linked to autoimmune diseases, but its association with Hashimoto's thyroiditis is infrequently reported.
• Patients with a single functioning kidney face unique challenges when managing conditions causing ureteral entrapment.

Purpose of the Study:

• To report a rare case of idiopathic RPF associated with Hashimoto's thyroiditis.
• To describe the management of RPF in a patient with a solitary kidney.
• To highlight the successful therapeutic approach involving corticosteroids and ureteral stenting.

Main Methods:

• A comprehensive literature review was performed to identify similar cases.
• Clinical data from the patient, including diagnostic imaging and laboratory results, were analyzed.
• Treatment involved corticosteroid therapy and temporary placement of a double-J ureteral stent.

Main Results:

• The patient presented with idiopathic RPF and coexisting Hashimoto's thyroiditis.
• The condition was complicated by the presence of a single functioning kidney.
• Successful management was achieved with corticosteroids and a double-J stent, resolving the ureteral entrapment.

Conclusions:

• Idiopathic RPF can occur in conjunction with Hashimoto's thyroiditis, even in patients with renal compromise.
• Corticosteroid therapy combined with ureteral stenting offers an effective treatment strategy for RPF with ureteral entrapment.
• This case underscores the importance of considering autoimmune associations in RPF and tailoring treatment to individual patient circumstances, particularly renal status.