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Related Concept Videos

Chronic Pancreatitis I: Introduction01:24

Chronic Pancreatitis I: Introduction

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The pancreas, an elongated and flat gland situated behind the stomach, serves a vital function in digesting food and managing blood sugar levels.
Pancreatitis is the inflammation of the pancreas, which occurs when the immune system becomes active and causes swelling, pain, and disruptions in organ function. Pancreatitis can manifest as either an acute or chronic condition.
Acute pancreatitis arises suddenly and lasts for a brief duration, while chronic pancreatitis is a long-term affliction...
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Acute Pancreatitis I: Introduction01:27

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Pancreatitis is inflammation of the pancreas, an organ located behind the stomach. It can be either acute or chronic.
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Chronic Pancreatitis II: Collaborative Care01:29

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The management of chronic pancreatitis is multifaceted, involving a comprehensive approach that includes thorough assessment, diagnostic testing, and a variety of management strategies.
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Acute pancreatitis presents a complex medical emergency characterized by rapid onset inflammation of the pancreas, demanding timely diagnosis and management to prevent complications. The condition primarily manifests through severe upper abdominal pain that often radiates to the back. This pain intensifies following the consumption of fatty foods. Accompanying symptoms such as nausea, vomiting, abdominal distention, fever, dyspnea, cyanosis, and jaundice can vary in intensity but significantly...
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The pancreas, an essential organ in the human body, is a pinkish-gray elongated structure located posterior to the stomach. It extends laterally from the duodenum towards the spleen and is firmly bound to the posterior wall of the abdominal cavity. The organ's surface has a lumpy, lobular texture that gives it a unique appearance.
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An Obstructive Chronic Pancreatitis Model Established Through Electrocoagulation
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Hereditary Pancreatitis.

Edgardo D Rivera Rivera, Ankur Chugh, Jonathon Cordova

    Pediatric Annals
    |February 16, 2016
    PubMed
    Summary
    This summary is machine-generated.

    Hereditary pancreatitis, a genetic condition, can cause severe pain. A total pancreatectomy with auto islet cell transplant successfully relieved pain and insulin dependence in a young patient.

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    Area of Science:

    • Gastroenterology and Genetics
    • Pediatric Pancreatology

    Background:

    • Hereditary pancreatitis is a rare genetic disorder characterized by recurrent episodes of acute pancreatitis.
    • A PRSS1 mutation is a common genetic cause, necessitating early diagnosis and management.
    • Family history is a critical factor in identifying at-risk individuals.

    Observation:

    • A 13-year-old male with a known PRSS1 mutation experienced worsening, life-disrupting pancreatitis pain.
    • Despite multidisciplinary management, his symptoms escalated, impacting daily activities.
    • Surgical intervention was considered after extensive evaluation and discussion.

    Findings:

    • A total pancreatectomy with autologous islet cell transplantation was performed.
    • The patient achieved complete pain relief post-surgery.
    • The patient no longer requires insulin therapy, indicating successful islet cell function.

    Implications:

    • Total pancreatectomy with autologous islet cell transplantation is a viable, curative option for severe hereditary pancreatitis.
    • Early diagnosis and a high index of clinical suspicion are crucial for managing hereditary pancreatitis.
    • This case highlights the importance of long-term multidisciplinary care and tailored treatment strategies for genetic pancreatic disorders.