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Updated: Mar 25, 2026

Therapy Interventions for Upper Limb Amputees Undergoing Selective Nerve Transfers

Therapy Interventions for Upper Limb Amputees Undergoing Selective Nerve Transfers

Published on: October 29, 2021

Factors affecting functional outcome after lower extremity amputation.

Abdullah Bin Saeed¹, Usama Bin Saeed², Muhammad Zain-Ur-Rehman²

¹Department of General Surgery, Allied Hospital, Punjab Medical College, Faisalabad.

JPMA. the Journal of the Pakistan Medical Association

|February 16, 2016

Summary

This summary is machine-generated.

Comorbidities like stroke and end-stage renal disease negatively impact functional outcomes after lower extremity amputations. Higher amputation levels and female gender also correlate with poorer functional status post-surgery.

Keywords:

Lower extremity amputation, Co-morbidities, Minimum data set, Recovery of function.

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Determining the Functional Status of the Corticospinal Tract Within One Week of Stroke

Determining the Functional Status of the Corticospinal Tract Within One Week of Stroke

Published on: February 22, 2020

Area of Science:

Orthopedics
Vascular Surgery
Rehabilitation Medicine

Background:

Over 100,000 major lower extremity amputations occur annually in the US.
Operative mortality remains stable at 9-10% despite outcome improvements.
Predictors for functional outcome in amputees are documented.

Purpose of the Study:

To assess the impact of comorbidities on functional status following lower extremity amputations.

Main Methods:

Prospective comparative study of 104 patients.
Patients grouped into trans-metatarsal (TM), below-knee (BK), and above-knee (AK) amputation categories.
Pre-amputation comorbidities included diabetes, coronary heart disease, chronic kidney disease, and congestive heart failure.

Main Results:

30-day mortality was 9%; 27.7% hospital readmission.
Stroke, end-stage renal disease (ESRD), and poor cognitive function predicted the worst outcomes.
BK and AK amputations did not achieve baseline function within 6 months.

Conclusions:

Higher amputation level, stroke history, ESRD, poor cognitive scores, and female gender are linked to worse functional status.
These factors are critical for managing amputee patient outcomes.
Further research may explore targeted interventions for high-risk groups.