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Updated: Mar 25, 2026

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High-throughput Screening for Broad-spectrum Chemical Inhibitors of RNA Viruses
Published on: May 5, 2014
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Specific Antivirulence Activity, A New Concept for Reliable Screening of Virulence Inhibitors
1Laboratory of Aquaculture and Artemia Reference Center, Ghent University, 9000 Gent, Belgium.
Trends in Biotechnology
|February 17, 2016
Abstract:
Antivirulence therapy, disarming pathogens rather than killing them, is emerging as a novel strategy for disease control. Reporter strains expressing an easily measurable and quantifiable phenotype enable easy screening of virulence inhibitors. In this paper I propose a novel concept to exclude false positives in this type of screening.

