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Related Concept Videos

Heart Failure VI: Adjunct Therapies01:22

Heart Failure VI: Adjunct Therapies

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Additional therapies for treating patients with heart failure (HF) may include procedural interventions, supplemental oxygen, the management of sleep disorders, and nutritional therapy.Procedural InterventionsImplantable Cardioverter-Defibrillator: For patients at risk of life-threatening arrhythmias due to severe left ventricular dysfunction, an Implantable Cardioverter-Defibrillator (ICD) can detect and terminate these arrhythmias, preventing sudden cardiac death and improving survival rates.
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Heart Failure VII: Nursing Interventions01:30

Heart Failure VII: Nursing Interventions

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The first step in nursing management of a patient with heart failure involves thoroughly assessing the patient's medical history.Subjective Data: Obtain the patient's medical history of coronary artery disease, hypertension, myocardial infarction, and symptoms like dyspnea, orthopnea, and paroxysmal nocturnal dyspnea.Objective Data: Conduct a physical examination to identify findings such as jugular vein distention, pulmonary crackles, tachycardia, murmurs, peripheral edema, and vital signs,...
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Heart Failure V: Medical Management01:30

Heart Failure V: Medical Management

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Medical Management of Acute Decompensated Heart Failure (ADHF)The primary goals of therapy for patients hospitalized with acute decompensated heart failure (ADHF) include:Relieving symptomsOptimizing volume statusSupporting oxygenation and ventilationMaintaining cardiac output (CO) and end-organ perfusionIdentifying and addressing the cause of ADHFPreventing complicationsProviding patient education on factors precipitating HF exacerbationPlanning for dischargeOngoing monitoring and assessment...
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Heart Failure III: Clinical Manifestations01:26

Heart Failure III: Clinical Manifestations

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Heart failure (HF) manifests primarily as dyspnea, fatigue, and fluid retention, resulting in peripheral and pulmonary edema. Symptoms may vary depending on which ventricle is more affected, left or right.Left-Sided Heart FailureAlso known as left ventricular failure, this condition results from the left ventricle's inability to fill or eject sufficient blood into the systemic circulation. It leads to pulmonary congestion, which occurs when the left ventricle fails to eject blood effectively...
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Heart Failure Drugs: Inhibitors of Renin-Angiotensin System01:26

Heart Failure Drugs: Inhibitors of Renin-Angiotensin System

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The activation of the sympathetic nervous system and the renin-angiotensin-aldosterone system (RAAS) contributes to cardiac remodeling, and inhibiting the RAAS is a pharmacological target in heart failure management. As a result, neurohumoral modulation is a crucial treatment principle for managing heart failure. This approach involves using medications like ACE inhibitors (ACEIs), angiotensin receptor blockers (ARBs), β-blockers, mineralocorticoid receptor antagonists (MRAs), and neutral...
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Heart Failure Drugs: β-Blockers01:22

Heart Failure Drugs: β-Blockers

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β-adrenergic antagonists, commonly known as β-blockers, block the effects of sympathetic neurotransmitters such as noradrenaline (NA) and adrenaline (ADR). They have several beneficial effects in heart failure treatment. They reduce heart rate, the force of contraction, and cardiac muscle relaxation. They also slow the atrial-ventricular conduction rate and raise the threshold for arrhythmias. The concentration of β-blockers determines their effects on bronchodilation,...
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Related Experiment Video

Updated: Mar 25, 2026

Cutoff Value of Phase Angle by Bioelectrical Impedance Analysis at Admission as a Prognostic Factor in Patients with Acute Heart Failure
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Cutoff Value of Phase Angle by Bioelectrical Impedance Analysis at Admission as a Prognostic Factor in Patients with Acute Heart Failure

Published on: June 10, 2025

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Nonadherence in the Advanced Heart Failure Population.

Jonathan Gandhi1, Andrew McCue1, Robert Cole2

  • 1Emory University School of Medicine, Emory University, 1365 Clifton Road NE, Atlanta, GA, 30322, USA.

Current Heart Failure Reports
|February 17, 2016
PubMed
Summary

Patient adherence is crucial for managing heart failure (HF). Nonadherence in advanced HF patients requires further study, focusing on objective adherence measurements like digital pills.

Keywords:
Heart failureHeart transplantLeft ventricular assist deviceNonadherence

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Area of Science:

  • Cardiology
  • Health Services Research

Background:

  • Over 5 million Americans live with heart failure (HF).
  • Nonadherence to treatment is common in HF, worsening outcomes and increasing costs.
  • Adherence is particularly critical for advanced HF patients (e.g., transplant, LVAD recipients).

Purpose of the Study:

  • To highlight the lack of data on nonadherence in advanced HF.
  • To emphasize the need for effective management strategies in this population.
  • To advocate for standardized definitions and objective adherence measurements in future HF research.

Main Methods:

  • Literature review and synthesis of existing data on HF adherence.
  • Identification of knowledge gaps concerning advanced HF patient adherence.
  • Discussion of novel adherence measurement technologies.

Main Results:

  • Significant data scarcity exists regarding nonadherence in advanced HF.
  • Current management strategies for nonadherence in this group are not well-defined.
  • Objective adherence measures, like digital pills, show promise for future research.

Conclusions:

  • Advanced HF patient adherence is understudied but critically important.
  • Future research must define adherence uniformly and employ objective measurement tools.
  • Improved understanding of adherence can lead to better outcomes and reduced healthcare burden in advanced HF.