Related Experiment Video

Updated: Mar 25, 2026

Analyses of Proteinuria, Renal Infiltration of Leukocytes, and Renal Deposition of Proteins in Lupus-prone MRL/lpr Mice
09:43

Analyses of Proteinuria, Renal Infiltration of Leukocytes, and Renal Deposition of Proteins in Lupus-prone MRL/lpr Mice

Published on: June 8, 2022

3.6K

Prevalence and correlates of proteinuria in Kampala, Uganda: a cross-sectional pilot study

Joseph Lunyera1,2, John W Stanifer3, Prossie Ingabire4

  • 1Duke Global Health Institute, Duke University, 310 Trent Drive, Durham, NC, USA. josephlunyera@gmail.com.

BMC Research Notes
|February 17, 2016
PubMed

Insights

A pilot study in Uganda found high rates of proteinuria, hypertension, and impaired fasting glucose among urban adults. This highlights the urgent need for more chronic kidney disease (CKD) research and awareness in sub-Saharan Africa.

Area of Science:

  • Nephrology
  • Public Health
  • Epidemiology

Background:

  • Chronic kidney disease (CKD) prevalence is rising in sub-Saharan Africa, yet awareness and access to care remain limited.
  • Few community-based CKD screenings have been conducted in Uganda, hindering early detection and management.
  • The Uganda Kidney Foundation organized a World Kidney Day screening event to address these challenges.

Purpose of the Study:

  • To conduct a pilot community-based screening for CKD risk factors in urban Uganda.
  • To assess the prevalence of proteinuria, hypertension, impaired fasting glucose, and obesity.
  • To raise awareness and facilitate further epidemiological studies on non-communicable diseases (NCDs) in Uganda.

Main Methods:

  • A cross-sectional pilot study was conducted in Kampala, Uganda, in March 2013.
  • Participants were recruited via mass media (radio, TV, newspapers) and public notices.
  • Screening included tests for proteinuria, hypertension, fasting glucose, and obesity.

Main Results:

  • 141 adult urban residents were enrolled; 64% were young adults (18-39 years).
  • High prevalence rates were observed: proteinuria (13%), hypertension (38%), and impaired fasting glucose (13%).
  • Proteinuria was notably higher in young adults and individuals with a history of alcohol intake.

Conclusions:

  • The study identified a significant prevalence of proteinuria among urban Ugandans, indicating a potential public health concern.
  • These findings underscore the critical need for increased CKD awareness and recognition in the region.
  • The results support the feasibility of conducting larger epidemiological studies on NCDs in Uganda.
Abstract

More Related Videos

Comparative Proteomic Analysis of Whole Kidney, Medulla, and Cortical Tubules in Diabetic Pathogenesis of Kidney Injury in Mice10:31

Comparative Proteomic Analysis of Whole Kidney, Medulla, and Cortical Tubules in Diabetic Pathogenesis of Kidney Injury in Mice

Published on: May 2, 2025

810
Unilateral Ureteral Obstruction Model for Investigating Kidney Interstitial Fibrosis04:37

Unilateral Ureteral Obstruction Model for Investigating Kidney Interstitial Fibrosis

Published on: April 25, 2025

1.8K

Related Concept Videos

Overview of Protein Metabolism01:21

Overview of Protein Metabolism

Proteins are broken down into amino acids during digestion. Unlike fats and carbohydrates, which are stored for later use, proteins are not. Instead, amino acids are either used to produce ATP through oxidation or contribute to the creation of new proteins for the growth and repair of the body. Any surplus amino acids from the diet are converted into glucose or triglycerides rather than excreted.
Amino acids play various roles in the body once they are absorbed into cells. They are restructured...
4.6K
Nephrotic Syndrome II : Assessment and Medical Management01:26

Nephrotic Syndrome II : Assessment and Medical Management

IntroductionNephrotic syndrome is a kidney disorder marked by excessive protein loss in the urine, leading to various systemic complications. This condition often results from damage to the glomeruli—the kidney's filtering units—causing proteinuria, low blood protein levels, and fluid retention. Understanding the assessment, diagnosis, and management of nephrotic syndrome is essential for effective treatment and prevention of further kidney damage.AssessmentPatient History: Document...
316
Chronic Kidney Disease I: Introduction01:25

Chronic Kidney Disease I: Introduction

Chronic Kidney Disease (CKD) arises when the kidneys progressively lose their ability to function, ultimately leading to end-stage renal disease. At this advanced stage, the kidneys can no longer filter waste or maintain essential body functions, requiring renal replacement therapy (RRT) through dialysis or a kidney transplant for survival.Early-stage chronic kidney disease and detection challengesIn CKD's early stages, symptoms often remain absent because healthy nephrons compensate for...
1.1K
Nephrotic Syndrome I : Introduction01:24

Nephrotic Syndrome I : Introduction

Nephrotic Syndrome is a chronic kidney disorder defined by clinical findings such as severe proteinuria, hypoalbuminemia, hyperlipidemia, and edema. These symptoms result from damage to the glomeruli, the kidney’s filtering units, increasing their permeability to proteins.Definition and Meaning:Proteinuria, defined as the loss of more than 3.5 grams of protein per day in adults, is a crucial feature of nephrotic syndrome. This condition is often accompanied by edema, the accumulation of...
950
Nursing Assessment of the Genitourinary System I: Health History01:21

Nursing Assessment of the Genitourinary System I: Health History

The genitourinary system is critical to maintaining fluid balance, waste elimination, and reproductive function. Nurses play a vital role in assessing this system, beginning with a thorough health history. This process involves gathering patient information, identifying risk factors, and recognizing symptoms of genitourinary disorders. Early detection is vital for timely interventions and management.1. Gathering Patient InformationA complete health history includes the patient’s personal,...
561
Urine Studies I: Urinalysis01:29

Urine Studies I: Urinalysis

Urinalysis is a widely used diagnostic test that analyzes urine's physical, chemical, and microscopic characteristics. Healthcare providers use it to detect and monitor various health conditions, including renal disease, urinary tract infections (UTIs), diabetes, and metabolic or systemic disorders.Components of UrinalysisUrinalysis consists of three primary components: physical, chemical, and microscopic examination. Each provides unique insights into the urine sample and, by extension, the...
2.1K