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Published on: July 28, 2018
"AVOID"ing harm by a double-edged sword: is there a role for ultrafiltration in heart failure?
1Division of Nephrology, Hypertension, and Renal Transplantation, University of Florida, Gainesville, Florida, USA.
Abstract:
Prior studies comparing ultrafiltration with medical management for acute decompensated heart failure have yielded conflicting results. The AVOID-HF trial was designed as a definitive comparison of optimal ultrafiltration versus optimal diuretic-based medical therapy; unfortunately, the trial was terminated prematurely because of slow recruitment. The results of AVOID-HF nevertheless provide a rationale for well-designed, adequately powered trials to determine whether ultrafiltration has a role in the routine management of acute decompensated heart failure.
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