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[Platelet antiaggregants in other pathologies].

R Jouve

    La Revue Du Praticien
    |November 1, 1989
    PubMed
    Summary
    This summary is machine-generated.

    Platelet aggregation inhibitors are used for various conditions, supported by clinical trials. These drugs are indicated for arterial diseases, vascular procedures, and certain blood disorders, with other potential uses under discussion.

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    Effects of cicletanine in the left circumflex coronary artery occlusion-reperfusion canine model of sudden death: analysis of 107 experiments using Cox's proportional hazards model.

    Drugs under experimental and clinical research·1988

    Area of Science:

    • Pharmacology
    • Hematology
    • Vascular Medicine

    Context:

    • Platelet aggregation inhibitors are widely prescribed based on the presumed role of platelets in various pathologies.
    • Clinical trials have established formal indications for these antiplatelet agents in specific medical scenarios.

    Purpose:

    • To outline the established and potential clinical indications for platelet aggregation inhibitors.
    • To review the evidence supporting the use of antiplatelet drugs in diverse conditions.

    Summary:

    • Established uses include peripheral artery disease (intermittent claudication, arterial leg ulcers), atherosclerosis progression, vascular graft implantation, diabetic retinopathy, retinal vein thrombosis, sickle cell anemia, and thrombocythemia.
    • The abstract lists specific conditions where platelet aggregation inhibitors are clinically applied.

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  • Additional, debated indications for antiplatelet therapy are also noted.

    • Impact:

    • Provides a comprehensive overview of current and emerging applications for antiplatelet medications.
    • Aids clinicians in understanding the evidence base for prescribing these agents.
    • Highlights areas for further research into platelet function and antiplatelet therapy.