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Related Concept Videos

Urinary Bladder01:23

Urinary Bladder

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The urinary bladder is a hollow, muscular sac that temporarily stores urine before it is expelled from the body. It can hold approximately 600 mL of urine prior to micturition. The bladder is retroperitoneal and located behind the pubic symphysis in the pelvic floor.
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Urination, or micturition involves the coordination of the bladder's detrusor muscle and two sphincters to ensure controlled bladder emptying.
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Anatomy of the Genitourinary System II: Bladder and Urethra01:19

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The lower urinary system consists of the urinary bladder and urethra, which are essential in storing and expelling urine from the body. Together with the internal and external sphincters, these structures work together to regulate urination effectively.Anatomy of the BladderThe urinary bladder is a muscular, stretchable organ behind the pubic bone and in front of the rectum. In females, the bladder is positioned anterior to the vagina and inferior to the uterus, while in males, it is located...
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Urodynamic Studies: Uroflowmetry01:19

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Uroflowmetry is a non-invasive urodynamic test designed to measure various aspects of urination, including volume, flow rate, and the time to void. This test is crucial for diagnosing and assessing conditions such as bladder outlet obstruction, bladder dysfunction, incomplete bladder emptying, incontinence, and urinary tract blockages caused by benign prostatic hyperplasia (BPH) and urethral strictures.Pre-Test Instructions:Before a uroflowmetry test, patients are typically advised to drink...
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Disorders of the Urinary System01:20

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The urinary system is responsible for eliminating waste and excess fluids from the body. However, disorders of the urinary system can arise due to various reasons like infections, stress, age, congenital abnormalities, and lifestyle.
Urinary tract infections (UTIs) are one of the most common urinary system disorders. They are caused by bacteria that enter the urethra and can spread to the bladder resulting in cystitis. Pyelonephritis is the result of a UTI that has ascended to the level of the...
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Disorders of the Autonomic Nervous System01:18

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The autonomic nervous system (ANS) is an intricate network of nerves that controls functions such as the regulation of heart rate, digestion, and blood pressure regulation. When this system malfunctions, it can lead to various disorders that affect multiple bodily functions. One common feature of many autonomic disorders is the involvement of smooth blood vessels, which play a crucial role in regulating blood flow throughout the body.
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Detrusor Underactivity Model in Rats by Conus Medullaris Transection
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Overactive Bladder.

Nicola White1, Cheryl B Iglesia2

  • 1Female Pelvic Medicine and Reconstructive Surgery, National Center for Advanced Pelvic Surgery, MedStar Washington Hospital Center, Georgetown University, 106 Irving Street, Northwest, Suite 405 South, Washington, DC 20010, USA.

Obstetrics and Gynecology Clinics of North America
|February 17, 2016
PubMed
Summary
This summary is machine-generated.

Millions with overactive bladder (OAB) have new treatment options. Therapies like botulinum toxin injections, nerve stimulation, and sacral neuromodulation offer symptom relief, improving quality of life.

Keywords:
AnticholinergicsBladder botulinum toxin (Botox) injectionOveractive bladderSacral neuromodulationUrinary incontinence

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Area of Science:

  • Urology
  • Nephrology

Background:

  • Overactive bladder (OAB) affects millions, impacting quality of life.
  • Anticholinergics are a primary treatment for OAB symptoms.
  • Emerging therapies offer alternatives for managing OAB.

Purpose of the Study:

  • To review current treatment options for overactive bladder (OAB).
  • To discuss the efficacy of various OAB interventions.
  • To highlight the growing number of management strategies for OAB patients.

Main Methods:

  • Review of existing literature on OAB treatments.
  • Comparison of anticholinergic therapy with newer interventions.
  • Discussion of botulinum toxin injections, percutaneous tibial nerve stimulation, and sacral neuromodulation.

Main Results:

  • Botulinum toxin injections demonstrate OAB symptom improvement comparable to anticholinergics.
  • Percutaneous tibial nerve stimulation effectively reduces urinary frequency and urge incontinence.
  • Sacral neuromodulation is FDA-approved for refractory OAB, urge incontinence, and urinary retention.

Conclusions:

  • Patients with OAB have an expanding array of treatment choices.
  • These alternative therapies can significantly improve symptom management and quality of life.
  • Further head-to-head comparisons are needed, but options are increasing for OAB patients.