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Updated: Mar 25, 2026

Transcranial Direct Current Stimulation tDCS for Memory Enhancement
Published on: September 18, 2021
Multisession Anodal tDCS Protocol Improves Motor System Function in an Aging Population
G Dumel1, M-E Bourassa1, M Desjardins1
1Centre de Recherche de l'Hôpital du Sacré-Cœur de Montréal, 5400 boulevard Gouin Ouest, Montréal, QC, Canada H4J 1C5; Département de Psychologie, Université du Québec à Montréal, 100 rue Sherbrooke Ouest, Montréal, QC, Canada H2X 3P2.
Objectives:
The primary objective of this study was to investigate the effects of five consecutive, daily 20-minute sessions of M1 a-tDCS on motor learning in healthy, cognitively intact, aging adults.
Design:
A total of 23 participants (51 to 69 years old) performed five consecutive, daily 20-minute sessions of a serial reaction time task (SRT task) concomitant with either anodal (n = 12) or sham (n = 11) M1 a-tDCS.
Results:
We found a significant group × training sessions interaction, indicating that whereas aging adults in the sham group exhibited little-to-no sequence-specific learning improvements beyond the first day of training, reproducible improvements in the ability to learn new motor sequences over 5 consecutive sessions were the net result in age-equivalent participants from the M1 a-tDCS group. A significant main effect of group on sequence-specific learning revealed greater motor learning for the M1 a-tDCS group when the five learning sessions were averaged.
Conclusion:
These findings raise into prominence the utility of multisession anodal TDCS protocols in combination with motor training to help prevent/alleviate age-associated motor function decline.
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