Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Video

Updated: Mar 25, 2026

Step By Step: Microsurgical training method combining two nonliving animal models
05:25

Step By Step: Microsurgical training method combining two nonliving animal models

Published on: May 9, 2015

16.1K

S1 guideline: microscopically controlled surgery (MCS).

Christoph R Löser1, Rainer Rompel2, Matthias Möhrle3

  • 1Hautklinik, Hauttumorzentrum Ludwigshafen.

Journal Der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG
|February 17, 2016
PubMed
Summary

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Adjunctive optical and magnetic stimulation for venous and mixed etiology leg ulcers: protocol for the NAZARÉ multicenter randomized controlled trial.

Trials·2026
Same author

Years of life lost in cutaneous squamous cell carcinoma: analysis of a prospective cohort of 1400 patients.

Journal of cancer research and clinical oncology·2026
Same author

Multi-omics analysis reveals dermokine as a regulator of keratinocyte differentiation and adhesion.

JCI insight·2026
Same author

[Treatment algorithm based on S1 guideline for the management of pincer nails (involuted nails)].

Dermatologie (Heidelberg, Germany)·2026
Same author

Treatment patterns in geriatric patients with melanoma and the effect of age on the efficacy of immunotherapy: Analysis from the real-world multicenter registry ADOREG.

European journal of cancer (Oxford, England : 1990)·2026
Same author

Effectiveness of Punch Grafting in Promoting Healing and Reducing Pain in Hard-to-Heal Leg Ulcers.

Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society·2026
Same journal

The different face of skin-rash induced by brentuximab vedotin.

Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG·2026
Same journal

Repositioning Non-Ablative Fractional Lasers - Molecular and Histological Insights from a scoping review.

Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG·2026
Same journal

Infusion-site reactions to foslevodopa/foscarbidopa in Parkinson's disease.

Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG·2026
Same journal

Tranexamic Acid-Soaked Intranasal Packing for Postoperative Bleeding After Nasal Interpolation Flap Repair.

Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG·2026
Same journal

Monoclonal gammopathy of dermatological significance: non-amyloid paraprotein deposits with light and heavy chains.

Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG·2026
Same journal

Papular epidermal nevus with "skyline" basal cell layer: Clinical clues from a three-member family.

Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG·2026
See all related articles
This summary is machine-generated.

Microscopically controlled surgery (MCS) with 3D histology ensures complete tumor removal (R0 resection) at difficult sites. This safe method offers superior or equivalent aesthetic outcomes compared to other treatments.

Area of Science:

  • Oncology
  • Surgical Pathology
  • Medical Technology

Background:

  • Complete examination of surgical margins is crucial for successful cancer treatment.
  • Achieving R0 resection (no tumor cells at the margin) is a key goal in oncologic surgery.
  • Problematic tumor sites present challenges for complete margin assessment and tissue preservation.

Purpose of the Study:

  • To evaluate microscopically controlled surgery (MCS) with 3D histology for R0 resection confirmation.
  • To compare the safety and aesthetic outcomes of MCS with alternative oncological procedures.
  • To highlight the benefits of MCS in preserving adjacent tissue during tumor removal.

Main Methods:

  • Utilizing 3D histology for complete examination of surgical margins.

More Related Videos

Piezo High Accuracy Surgical Osteal Removal PHASOR: A Technique for Improved Cranial Window Surgery in Mice
06:09

Piezo High Accuracy Surgical Osteal Removal PHASOR: A Technique for Improved Cranial Window Surgery in Mice

Published on: March 2, 2018

11.3K
Microdissection of the Rodent Eye
11:03

Microdissection of the Rodent Eye

Published on: April 21, 2023

6.9K

Related Experiment Videos

Last Updated: Mar 25, 2026

Step By Step: Microsurgical training method combining two nonliving animal models
05:25

Step By Step: Microsurgical training method combining two nonliving animal models

Published on: May 9, 2015

16.1K
Piezo High Accuracy Surgical Osteal Removal PHASOR: A Technique for Improved Cranial Window Surgery in Mice
06:09

Piezo High Accuracy Surgical Osteal Removal PHASOR: A Technique for Improved Cranial Window Surgery in Mice

Published on: March 2, 2018

11.3K
Microdissection of the Rodent Eye
11:03

Microdissection of the Rodent Eye

Published on: April 21, 2023

6.9K
  • Performing microscopically controlled surgery (MCS) for infiltrating tumor resection.
  • Comparing outcomes with cryosurgery, short-range irradiation, and photodynamic therapy (PDT).

    • Main Results:

    • MCS with 3D histology enables safe and complete R0 resection of infiltrating tumors.
    • The technique is particularly effective at challenging tumor locations.
    • Aesthetic results were excellent or good, outperforming or matching non-surgical methods.

    Conclusions:

    • Microscopically controlled surgery (MCS) is a safe and effective method for achieving R0 resection.
    • 3D histology provides complete margin examination, enhancing surgical confidence.
    • MCS offers superior or equivalent aesthetic outcomes, making it a preferred oncological procedure.