Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Oxidation of Alkenes: Syn Dihydroxylation with Potassium Permanganate02:21

Oxidation of Alkenes: Syn Dihydroxylation with Potassium Permanganate

17.9K
Alkenes can be dihydroxylated using potassium permanganate.  The method encompasses the reaction of an alkene with a cold, dilute solution of potassium permanganate under basic conditions to form a cis-diol along with a brown precipitate of manganese dioxide.
17.9K
Oxidation of Alcohols02:37

Oxidation of Alcohols

18.1K
In this lesson, the oxidation of alcohols is discussed in depth. The various reagents used for oxidation of primary and secondary alcohols are detailed, and their mechanism of action is provided.
The process of oxidation in a chemical reaction is observed in any of the three forms:
18.1K
Radical Oxidation of Allylic and Benzylic Alcohols01:21

Radical Oxidation of Allylic and Benzylic Alcohols

3.1K
Activated manganese(IV) oxide can selectively oxidize allylic and benzylic alcohols via a radical intermediate mechanism. Primary allylic alcohols are oxidized to aldehydes, while secondary allylic alcohols yield ketones. The redox reaction of potassium permanganate with an Mn(II) salt such as manganese sulfate (under either alkaline or acidic conditions), followed by thorough drying, yields the oxidizing agent: activated MnO2. While MnO2 is insoluble in the solvents used for the reaction, the...
3.1K
Oxidation of Alkenes: Syn Dihydroxylation with Osmium Tetraoxide02:44

Oxidation of Alkenes: Syn Dihydroxylation with Osmium Tetraoxide

13.4K
Alkenes are converted to 1,2-diols or glycols through a process called dihydroxylation. It involves the addition of two hydroxyl groups across the double bond with two different stereochemical approaches, namely anti and syn. Dihydroxylation using osmium tetroxide progresses with syn stereochemistry.
13.4K
Oxidation and Reduction of Organic Molecules01:19

Oxidation and Reduction of Organic Molecules

10.2K
Energy production within a cell involves many coordinated chemical pathways. Most of these pathways are combinations of oxidation and reduction reactions, which occur at the same time. An oxidation reaction strips an electron from an atom in a compound, and the addition of this electron to another compound is a reduction reaction. Because oxidation and reduction usually occur together, these pairs of reactions are called redox reactions.
The removal of an electron from a molecule, results in a...
10.2K
Oxidation-Reduction Reactions03:11

Oxidation-Reduction Reactions

77.8K
Oxidation–Reduction Reactions
77.8K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Ethical considerations and management strategies for fertility preservation in women of reproductive age with malignant tumors: Chinese practices and perspectives.

Frontiers in endocrinology·2026
Same author

Ultra-Stable 2D Magneto-Fluorescent Probe-Mediated Multiplex Immunochromatographic Assay for Precise Bedside Detection of Sepsis.

ACS nano·2026
Same author

Transcriptome and metabolome analysis reveals that cuproptosis in bovine cumulus cells triggers the intercellular transmission of senescence and mitochondrial dysfunction to impair oocyte quality.

Theriogenology·2026
Same author

LncRNA7503 decreases peach (Prunus persica) branch number and angle by inducing pre-miR395a degradation and reducing bioactive BR content.

Molecular horticulture·2026
Same author

Direct/enrichment dual-mode lateral flow immunoassay enabled by a composite magnetic-fluorescent nanolabel for ultrasensitive detection of Helicobacter pylori.

Mikrochimica acta·2026
Same author

PpBRC1 negatively regulates branching via modulating GA signal transduction gene PpGID1b in peach (Prunus persica).

Plant cell reports·2026
Same journal

Data-Driven Exploration of the Polyethylene Catalyst Chemical Space via Machine Learning.

The journal of physical chemistry letters·2026
Same journal

Role of Ultrafast Electron-Thermal-Phonon Interactions in High Harmonic Generation and Dephasing from Graphene.

The journal of physical chemistry letters·2026
Same journal

Real-Time Vibrational Spectroscopy Reveals an Inversion Transition State in the Photoisomerization of Phenylazoimidazole.

The journal of physical chemistry letters·2026
Same journal

Precursor-Directed Self-Assembly in Hydrothermal Carbon Nitride Nanostructures Revealed by Nano-FTIR.

The journal of physical chemistry letters·2026
Same journal

Correction to "Equation-of-Motion Block-Correlated Coupled Cluster Method for Excited Electronic States of Strongly Correlated Systems".

The journal of physical chemistry letters·2026
Same journal

Rationalizing Stacking-Dependent Charge Injection Dynamics in Radical-Based Organic Light-Emitting Diodes.

The journal of physical chemistry letters·2026
See all related articles

Related Experiment Video

Updated: Mar 25, 2026

Scalable Syntheses of Graphene Oxide and Reduced Graphene Oxide using Cascade Design Oxidation and Highly Basic Reduction Reactions
08:57

Scalable Syntheses of Graphene Oxide and Reduced Graphene Oxide using Cascade Design Oxidation and Highly Basic Reduction Reactions

Published on: July 3, 2025

2.4K

Substrate-Sensitive Graphene Oxidation.

Zhuhua Zhang1, Jun Yin1, Xiaofei Liu1

  • 1State Key Laboratory of Mechanics and Control of Mechanical Structures, Key Laboratory for Intelligent Nano Materials and Devices of the Ministry of Education, and Institute of Nanoscience, Nanjing University of Aeronautics and Astronautics , Nanjing 210016, China.

The Journal of Physical Chemistry Letters
|February 18, 2016
PubMed
Summary
This summary is machine-generated.

Graphene’s stability depends on its substrate. Metal substrates promote graphene oxidation, while bilayer graphene offers superior resistance, crucial for durable nanoelectronics.

More Related Videos

Visible-light Induced Reduction of Graphene Oxide Using Plasmonic Nanoparticle
07:24

Visible-light Induced Reduction of Graphene Oxide Using Plasmonic Nanoparticle

Published on: September 22, 2015

14.9K
Development and Functionalization of Electrolyte-Gated Graphene Field-Effect Transistor for Biomarker Detection
07:51

Development and Functionalization of Electrolyte-Gated Graphene Field-Effect Transistor for Biomarker Detection

Published on: February 1, 2022

3.9K

Related Experiment Videos

Last Updated: Mar 25, 2026

Scalable Syntheses of Graphene Oxide and Reduced Graphene Oxide using Cascade Design Oxidation and Highly Basic Reduction Reactions
08:57

Scalable Syntheses of Graphene Oxide and Reduced Graphene Oxide using Cascade Design Oxidation and Highly Basic Reduction Reactions

Published on: July 3, 2025

2.4K
Visible-light Induced Reduction of Graphene Oxide Using Plasmonic Nanoparticle
07:24

Visible-light Induced Reduction of Graphene Oxide Using Plasmonic Nanoparticle

Published on: September 22, 2015

14.9K
Development and Functionalization of Electrolyte-Gated Graphene Field-Effect Transistor for Biomarker Detection
07:51

Development and Functionalization of Electrolyte-Gated Graphene Field-Effect Transistor for Biomarker Detection

Published on: February 1, 2022

3.9K

Area of Science:

  • Materials Science
  • Surface Chemistry
  • Nanotechnology

Background:

  • Graphene's inertness is key for device durability.
  • Substrate interactions significantly influence graphene's chemical properties, an often-overlooked factor.

Purpose of the Study:

  • To investigate how different substrates affect graphene's susceptibility to oxidation.
  • To identify substrate characteristics that enhance or mitigate graphene oxidation.

Main Methods:

  • Utilized first-principles calculations to analyze electronic interactions.
  • Conducted experimental studies to validate theoretical predictions.
  • Examined graphene oxidation rates on various substrates including SiO2, hexagonal boron nitride, and metal substrates (Ni, Co, Cu).

Main Results:

  • Graphene remains inert on SiO2 and hexagonal boron nitride.
  • Metal substrates, particularly Ni and Co, induce significant graphene oxidation due to charge transfer and chemical interactions.
  • Copper substrates dramatically enhance oxygen diffusion on graphene.
  • Bilayer graphene demonstrates high oxidation resistance irrespective of the substrate.

Conclusions:

  • Substrate choice critically impacts graphene's chemical stability and oxidation resistance.
  • Bilayer graphene is a promising material for robust nanoelectronic applications.
  • Understanding substrate-mediated chemical functionalization is vital for designing advanced 2D material devices.