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Cerebral venous thrombosis in a patient with Crohn's disease

Young-Hak Cho1, Min Kyu Chae1, Jae Myung Cha1

  • 1Department of Internal Medicine, Kyung Hee University Hospital at Gangdong, Kyung Hee University School of Medicine, Seoul, Korea.

Intestinal Research
|February 18, 2016
PubMed

Insights

Patients with inflammatory bowel disease (IBD) face higher risks of blood clots. This case highlights a rare instance of cerebral venous thrombosis in a Crohn's disease patient, successfully treated with anticoagulation.

Area of Science:

  • Neurology
  • Gastroenterology
  • Hematology

Background:

  • Inflammatory bowel disease (IBD) patients exhibit increased venous thromboembolism (VTE) risk.
  • Common VTE sites in IBD include leg deep veins, pulmonary, portal, and mesenteric systems.
  • Cerebral venous thrombosis (CVT) is an uncommon complication in IBD patients.

Purpose of the Study:

  • To report a rare case of cerebral venous thrombosis in a patient with Crohn's disease.
  • To emphasize the importance of considering CVT in active IBD patients.
  • To illustrate the efficacy of anticoagulation in managing CVT in IBD.

Main Methods:

  • Case report of a 17-year-old female with Crohn's disease presenting with neurological symptoms.
  • Diagnostic imaging included magnetic resonance imaging with venography to confirm cerebral venous thrombosis.
  • Treatment involved initial intravenous heparin followed by oral rivaroxaban.

Main Results:

  • Cerebral venous thrombosis was diagnosed in cortical veins, superior sagittal sinus, right transverse sinus, and right internal jugular vein.
  • Anticoagulation therapy led to complete resolution of thrombosis and recanalization within two weeks.
  • The patient remained neurologically intact and completed six months of anticoagulant therapy.

Conclusions:

  • Cerebral venous thrombosis, though rare, should be considered in active inflammatory bowel disease patients presenting with relevant symptoms.
  • Prompt anticoagulation is crucial for preventing severe complications and ensuring favorable outcomes.
  • Early diagnosis and management can lead to successful recovery without long-term sequelae.

Keywords:
AnticoagulationCerebral venous thrombosisComplicationCrohn diseaseInflammatory bowel diseases

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