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Related Concept Videos

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The cultivation of environmental microorganisms has long been hindered by the inability to replicate complex native conditions in vitro. The isolation chip (iChip) addresses this limitation by facilitating the growth of previously uncultivable microorganisms through in situ incubation. Designed for high-throughput microbial cultivation, the iChip comprises hundreds of microchambers, each capable of housing a single microbial cell. These microchambers are loaded with a mixture of molten agar and...
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Culture shapes how people approach attraction, choose partners, and build long-term relationships. While some preferences in mate selection appear consistent across cultures, such as men valuing physical attractiveness and women emphasizing financial resources, cultural contexts influence how these preferences are expressed and prioritized. Marriage extends beyond romantic ideals in many societies and is deeply embedded in social, economic, and religious frameworks.The Role of Culture in Mate...
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One center experience in China.

Yunpeng Ling1, Xi Liu2, Yu Chen2

  • 1Department of Cardiac Surgery, Peking University Third Hospital Beijing 100049, China.

International Journal of Clinical and Experimental Medicine
|February 18, 2016
PubMed
Summary
This summary is machine-generated.

Off-pump coronary artery bypass grafting (OPCAB) shows satisfactory outcomes for patients with coronary artery disease and low ejection fraction. Left ventricular ejection fraction (LVEF) ≤30% and recent myocardial infarction are key risk factors for long-term survival.

Keywords:
Low eject fractionartery bypass graftingoff-pumpsurvival analysis

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Area of Science:

  • Cardiology
  • Cardiac Surgery
  • Vascular Surgery

Background:

  • Coronary artery disease (CAD) with low left ventricular ejection fraction (LVEF ≤40%) presents a significant surgical challenge.
  • Off-pump coronary artery bypass grafting (OPCAB) is an alternative surgical strategy for these high-risk patients.

Purpose of the Study:

  • To evaluate the long-term outcomes of OPCAB in patients with CAD and severely reduced LVEF (≤40%).
  • To identify independent prognostic factors influencing survival after OPCAB in this patient cohort.

Main Methods:

  • A retrospective analysis of 71 patients with LVEF ≤40% who underwent OPCAB between 2001 and 2004.
  • Kaplan-Meier survival analysis, log-rank tests, and Cox regression modeling were employed to assess long-term results and risk factors.

Main Results:

  • The mean follow-up duration was 64.9 months. Perioperative mortality was 8.5% (6/71).
  • The overall survival rates at 1, 3, 5, and 8 years were 95.1%, 93.3%, 86.3%, and 77.7%, respectively.
  • Cox regression identified LVEF ≤30% (RR=6.446) and acute myocardial infarction within 30 days (RR=5.993) as independent predictors of cardiac-related death.

Conclusions:

  • OPCAB can achieve satisfactory long-term outcomes in carefully selected patients with CAD and low LVEF.
  • Pre-existing LVEF ≤30% and recent acute myocardial infarction are critical risk factors impacting long-term survival post-OPCAB.