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Published on: August 25, 2019
Prognostic value of three pro-nuclei (3PN) incidence in elective single blastocyst-stage embryo transfer
Mingzhao Li1, Wanqiu Zhao1, Wei Li1
1The ART Center, Northwest Women's and Children's Hospital Xi'an 710003, China.
Objectives:
To investigate whether 3PN incidence could lead to a worse pregnancy outcome of elective single blastocyst stage embryo transfer (eSBET).
Methods:
This study included 706 eSBET cycles from January 2013 to March 2015. The patients were divided into two groups as follows: group 1 included 286 patients with no 3PN zygotes and group 2 included 420 patients with 3PN zygotes.
Main Outcome Measure:
female age, endometrial thickness, infertility duration, type of infertility, main etiology of infertility, clinical pregnancy and abortion rate.
Results:
We observed that there was no significant difference in female age, endometrial thickness, infertility duration and abortion rate between two groups. It's worth noting that the clinical pregnancy rate in 3PN > 0% group was significantly lower than 3PN = 0 group (P = 0.021).
Conclusions:
3PN incidence might make anegative effect on pregnancy outcomes in elective single blastocyst stage embryo transfer.
