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Isolated third ventricle glioblastoma.

Baran Yılmaz1, Murat Şakir Ekşi2, Mustafa Kemal Demir3

  • 1Department of Neurosurgery, Medical Faculty, Bahçeşehir University, Istanbul, Turkey.

Springerplus
|February 18, 2016
PubMed
Summary

This report details a rare case of isolated third ventricular glioblastoma in a 36-year-old woman. Prompt diagnosis and treatment, including surgery, radiotherapy, and chemotherapy, led to a favorable outcome.

Keywords:
BiopsyGlioblastomaHydrocephalusThird ventricleVentriculo-peritoneal shunt

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Area of Science:

  • Neuro-oncology
  • Neurosurgery
  • Neuropathology

Background:

  • Glioblastoma is a highly malignant primary brain tumor.
  • Typically found in cerebral hemispheres, glioblastomas rarely present in the third ventricle.
  • This case highlights an unusual isolated third ventricular glioblastoma presentation.

Purpose of the Study:

  • To report a rare case of isolated third ventricular glioblastoma.
  • To discuss the diagnostic and management challenges.
  • To evaluate the effectiveness of multimodal treatment.

Main Methods:

  • A 36-year-old female presented with symptoms of increased intracranial pressure.
  • Diagnostic imaging revealed a third ventricular mass with obstructive hydrocephalus.
  • Treatment involved stereotactic biopsy, shunt placement, radiotherapy, and chemotherapy.

Main Results:

  • Histopathological diagnosis confirmed glioblastoma.
  • Obstructive hydrocephalus was successfully managed.
  • The patient showed positive response to adjuvant therapy with resolution of hydrocephalus.

Conclusions:

  • Isolated third ventricular glioblastomas require prompt diagnosis and management.
  • Multimodal treatment including surgery, radiotherapy, and chemotherapy is effective.
  • This approach offers a safe and effective strategy for this rare tumor presentation.