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Strength in Numbers: Visualizing CTL-Mediated Killing In Vivo
1Department of Molecular Microbiology and Immunology, Oregon Health and Science University, Portland, OR 97239, USA.
Immunity
|February 18, 2016
Abstract:
Cytotoxic CD8+ T lymphocytes (CTLs) have long been believed to be extremely efficient killers. Forster and colleagues (Halle et al., 2016) used in vivo imaging to tell a different story, in which each CTL killed only 2-16 targets a day, and several CTLs per target were needed to get the job done.

