Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Tonsillitis II: Management01:26

Tonsillitis II: Management

548
This lesson will focus on the different treatment options for managing tonsillitis, which typically depend on the cause and severity.
548
Hand hygiene01:23

Hand hygiene

6.5K
Asepsis is the practice of preventing or breaking the chain of infection. The nurse employs aseptic techniques to prevent the spread of microorganisms and reduce the risk of diseases. Hand hygiene is the cornerstone of aseptic techniques and is classified into medical and surgical asepsis. Medical asepsis includes hand hygiene and the use of gloves. Surgical asepsis, or the sterile technique, refers to practices that render and keep objects and areas free of microorganisms.
Hand washing...
6.5K
Acute Pyelonephritis II: Diagnostic Studies and Management01:28

Acute Pyelonephritis II: Diagnostic Studies and Management

628
Introduction:For diagnosing acute pyelonephritis, a comprehensive patient history is collected to identify symptoms such as dysuria, frequent or urgent urination, flank pain, or costovertebral angle (CVA) tenderness that may suggest a kidney infection.Physical ExaminationDuring the physical examination, CVA tenderness is assessed. This involves gentle percussion over the costovertebral angle, where tenderness often indicates a kidney infection.Diagnostic TestsUrinalysis: Used to identify white...
628
Urinary Tract Infection III: Diagnostic Studies and Interprofessional Care01:30

Urinary Tract Infection III: Diagnostic Studies and Interprofessional Care

393
A healthcare provider can diagnose a urinary tract infection (UTI) through several methods:Medical History and Symptoms: The provider will take a detailed medical history and ask about symptoms such as frequent urination, burning sensation during urination, and lower abdominal pain.Urinalysis: A clean-catch urine sample is collected in a sterile container and tested for the presence of bacteria, white blood cells (leukocytes), nitrites, blood, and protein. The presence of leukocytes and...
393
Peptic Ulcer Disease IV: Management01:26

Peptic Ulcer Disease IV: Management

627
Medical treatment strategies for peptic ulcers encompass various methods. The primary goal of treatment is to diminish gastric acidity and strengthen mucosal defense mechanisms.
The therapeutic approach involves ensuring adequate rest, implementing drug therapy, promoting smoking cessation, making dietary modifications, and emphasizing long-term follow-up care.
Pharmacological management
The prevailing therapy for peptic ulcers involves a combination of managing the patient's current...
627
Endocarditis III: Medical Management01:18

Endocarditis III: Medical Management

329
Infective endocarditis management involves a multifaceted approach encompassing infection prevention, lifestyle modifications, pharmacological therapy, and surgical management.Infection Prevention:Hand Hygiene: Thorough handwashing is crucial to prevent the spread of infection. Hand hygiene should be performed regularly, especially before and after using the restroom.Oral Hygiene: Good oral hygiene is essential. It includes brushing teeth immediately after waking up and before bed, flossing...
329

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Low-dose isotretinoin for difficult-to-treat rosacea: Enough evidence to be convinced-What's next?

Journal of the European Academy of Dermatology and Venereology : JEADV·2025
Same author

You wait ages, and then two arrive at once: reporting guidelines should not be like buses.

Journal of clinical epidemiology·2025
Same author

A Systematic Review of Dental Antibiotic Stewardship Interventions.

Community dentistry and oral epidemiology·2024
Same author

Letter to the Editor regarding, "Clinical benefits of immediate dentin sealing: A systematic review and meta-analysis" by Alghuali et al.

The Journal of prosthetic dentistry·2024
Same author

Developing reporting checklist items from systematic review findings: a roadmap and lessons to be learned from ACCORD.

Journal of clinical epidemiology·2024
Same author

Tuning up the chords of consensus research with the ACcurate COnsensus Reporting Document (ACCORD).

The British journal of dermatology·2024
Same journal

Interventions to prevent or cease electronic cigarette use in children and adolescents.

The Cochrane database of systematic reviews·2026
Same journal

Drugs to improve anaemia, quality of life, and physical function in people with myelodysplastic syndromes (MDS).

The Cochrane database of systematic reviews·2026
Same journal

Interventions for smoking cessation in inpatient psychiatry settings.

The Cochrane database of systematic reviews·2026
Same journal

Mechanical thromboprophylaxis for preventing intradialytic hypotension in people undergoing maintenance haemodialysis.

The Cochrane database of systematic reviews·2026
Same journal

Prognostic models for predicting intensive care unit admission or mortality in critically ill adults not yet been admitted to the intensive care unit.

The Cochrane database of systematic reviews·2026
Same journal

Views and experiences of weight management for people living with mobility‑limiting conditions, intellectual disabilities or severe mental illness: a qualitative evidence synthesis.

The Cochrane database of systematic reviews·2026
See all related articles

Related Experiment Video

Updated: Mar 25, 2026

Author Spotlight: Enhancing Dental Pulp Research with Improved Mouse Models
05:16

Author Spotlight: Enhancing Dental Pulp Research with Improved Mouse Models

Published on: October 27, 2023

2.0K

Antibiotic use for irreversible pulpitis.

Anirudha Agnihotry1, Zbys Fedorowicz, Esther J van Zuuren

  • 1Section of Restorative Dentistry, UCLA School of Dentistry, 10833 Le Conte Avenue, Los Angeles, USA, CA 90095-1668.

The Cochrane Database of Systematic Reviews
|February 18, 2016
PubMed
Summary
This summary is machine-generated.

Systemic antibiotics do not significantly reduce pain for irreversible pulpitis. More research is needed to determine their effectiveness in managing this dental condition.

More Related Videos

Adjunctive Diode Laser Therapy and Probiotic Lactobacillus Therapy in the Treatment of Periodontitis and Peri-Implant Disease
06:06

Adjunctive Diode Laser Therapy and Probiotic Lactobacillus Therapy in the Treatment of Periodontitis and Peri-Implant Disease

Published on: May 9, 2022

3.3K
Inducing Apical Periodontitis in Mice
10:26

Inducing Apical Periodontitis in Mice

Published on: August 6, 2019

13.2K

Related Experiment Videos

Last Updated: Mar 25, 2026

Author Spotlight: Enhancing Dental Pulp Research with Improved Mouse Models
05:16

Author Spotlight: Enhancing Dental Pulp Research with Improved Mouse Models

Published on: October 27, 2023

2.0K
Adjunctive Diode Laser Therapy and Probiotic Lactobacillus Therapy in the Treatment of Periodontitis and Peri-Implant Disease
06:06

Adjunctive Diode Laser Therapy and Probiotic Lactobacillus Therapy in the Treatment of Periodontitis and Peri-Implant Disease

Published on: May 9, 2022

3.3K
Inducing Apical Periodontitis in Mice
10:26

Inducing Apical Periodontitis in Mice

Published on: August 6, 2019

13.2K

Area of Science:

  • Endodontics
  • Pharmacology
  • Evidence-based dentistry

Background:

  • Irreversible pulpitis causes severe dental pain, often leading to emergency dental visits.
  • Standard treatment involves pulp removal and root canal cleaning; however, antibiotics are sometimes prescribed for pain relief.
  • This review updates previous findings on antibiotic use for irreversible pulpitis.

Purpose of the Study:

  • To assess the efficacy of systemic antibiotics in managing pain associated with irreversible pulpitis.

Main Methods:

  • Systematic review of randomized controlled trials comparing systemic antibiotics plus analgesics versus placebo plus analgesics.
  • Searches conducted across multiple databases including Cochrane, MEDLINE, and EMBASE up to January 2016.
  • One trial, involving 40 participants and assessed as low risk of bias, was included; data synthesis was descriptive due to inability to pool results.

Main Results:

  • The evidence quality was rated as low.
  • No significant difference in pain reduction or analgesic use (ibuprofen, Tylenol) was observed between the penicillin and placebo groups.
  • Insufficient evidence exists to support or refute the benefit of penicillin for pain intensity in irreversible pulpitis.

Conclusions:

  • Current evidence from one small trial is insufficient to determine if antibiotics reduce pain for irreversible pulpitis.
  • Larger, methodologically sound trials are necessary to provide definitive evidence on the role of preoperative antibiotics in irreversible pulpitis treatment outcomes.