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Published on: March 25, 2021
Psychiatric Symptoms Associated with Oocyte-Donation
Ashraf Kazemi1, Maryam Zivari Delavar2, Gholamreza Kheirabadi3
1Reproductive Health Department, Nursing and Midwifery Care Research Center, School of Nursing and Midwifery, Isfahan University of Medical Sciences, Hezarjerib Av., Isfahan, Iran. Kazemi@nm.mui.ac.ir.
Oocyte donation is generally safe, but egg retrieval can increase anxiety and hypochondriasis in donors. Women donating eggs experienced higher levels of these symptoms post-procedure compared to controls.
Area of Science:
- Reproductive Medicine
- Psychiatry
- Women's Health
Background:
- Oocyte donation is a common fertility treatment.
- While generally safe, potential psychological impacts on donors are not fully understood.
- Previous research indicates a need to explore donor well-being.
Purpose of the Study:
- To prospectively evaluate psychiatric symptoms in oocyte donors versus controls.
- To assess changes in hypochondriasis, anxiety, social impairment, and depression.
- To compare psychological well-being before and after ovulation induction and oocyte retrieval.
Main Methods:
- Prospective study design.
- Involved 63 oocyte-donating women and 63 control women (providing own oocytes).
- Evaluated hypochondriasis, anxiety, social impairment, and depression pre- and post-ovulation induction.
Main Results:
- Oocyte donors had lower initial hypochondriasis scores than controls.
- Post-procedure, oocyte donors showed significantly increased hypochondriasis and anxiety scores.
- Depression scores remained similar between groups before and after the procedure.
Conclusions:
- Oocyte donation is safe, but the ovulation induction and retrieval process can negatively impact donor psychological health.
- Donors experience increased hypochondriasis and anxiety after oocyte retrieval.
- Further attention to donor mental health is warranted during assisted reproductive technology procedures.
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