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NEW APPLICATIONS OF ADAPTOGENS TO REDUCE RADIATION SIDE EFFECTS.
Wiadomosci Lekarskie (Warsaw, Poland : 1960)
|February 19, 2016
Summary
Reindeer and moose antler extracts show radioprotective properties, stimulating hematopoietic system recovery after irradiation. "Epsorin," derived from reindeer antlers, demonstrated the most significant positive impact on radiation-induced damage.
Area of Science:
- Radiology
- Immunology
- Pharmacology
Background:
- Ionizing radiation poses significant risks to the immune and hematopoietic systems.
- Environmental concerns in regions like Yakutia, due to radioactive deposits, highlight the need for radioprotective agents.
- Adaptogens are being explored for their potential therapeutic benefits.
Purpose of the Study:
- To investigate the radioprotective effects of specific adaptogens on the hematopoietic system.
- To evaluate the efficacy of reindeer and moose antler extracts in mitigating radiation damage.
- To identify the most potent adaptogen for hematopoietic protection.
Main Methods:
- Irradiation of hybrid mice using a RUM-25 radiological apparatus.
- Assessment of bone marrow, spleen, and thymus cellularity post-irradiation.
- Evaluation of early hematopoiesis functional activity using the exogenous colony-forming unit (CFU) method.
Main Results:
- Reindeer and moose antler extracts demonstrated a stimulatory effect on hematopoietic precursor cell activity following irradiation.
- The study medication promoted regeneration in the thymus and bone marrow.
- Adaptogen extracts significantly enhanced the functional activity of colony-forming units (CFUs).
Conclusions:
- Extracts from reindeer and moose antlers possess significant radioprotective properties.
- Reindeer antler extract "Epsorin" exhibited the most pronounced positive effect on hematopoietic recovery.
- These findings suggest adaptogens as a promising therapeutic strategy for mitigating radiation-induced hematopoietic damage.
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