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Lymphoma relapse presenting as neurolymphomatosis
1Department of Neurosurgery, Royal Melbourne Hospital, Melbourne, Victoria 3050, Australia.
Asian Journal of Neurosurgery
|February 19, 2016
Summary
Neurolymphomatosis (NL), a rare lymphoma complication, can mimic other neuropathies. Early diagnosis requires considering NL and using imaging with lumbar puncture, especially during rapid neurological decline.
Area of Science:
- Neurology
- Oncology
- Pathology
Background:
- Neurolymphomatosis (NL) is a rare neurological complication of lymphoma.
- It involves malignant lymphoma cells infiltrating nerves or nerve roots.
Observation:
- Presents the first Australian case of relapsed mantle cell lymphoma initially presenting as NL.
- Clinical and imaging findings of NL often mimic other neuropathies, posing diagnostic challenges.
Findings:
- NL can lead to delayed diagnosis and management due to its mimicry of other neuropathies.
- A high index of suspicion is crucial for diagnosing NL.
Implications:
- Emphasizes considering NL in differential diagnoses for unexplained neuropathies.
- Highlights the importance of combining imaging with lumbar puncture for NL diagnosis, especially in acute neurological deterioration.
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