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Updated: Mar 25, 2026

Polymalic Acid-based Nano Biopolymers for Targeting of Multiple Tumor Markers: An Opportunity for Personalized Medicine?
14:20

Polymalic Acid-based Nano Biopolymers for Targeting of Multiple Tumor Markers: An Opportunity for Personalized Medicine?

Published on: June 13, 2014

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Novel strategies for molecular targeting to cancer

Jun-Ping Liu1,2,3,4

  • 1Institute of Ageing Research, Hangzhou Normal University School of Medicine, Hangzhou, Zhejiang Province, China.

Clinical and Experimental Pharmacology & Physiology
|February 19, 2016
PubMed

Insights

This review highlights research on cancer drug resistance, invasion, and metastasis mechanisms. It covers genetic, genomic, and immunological changes, plus novel drug candidates for various cancers.

Area of Science:

  • Oncology
  • Pharmacology
  • Cancer Biology

Background:

  • This editorial reviews CEPP's 2014-2015 publications on cancer drug resistance, invasion, and metastasis.
  • It focuses on genetic, genomic, and immunological factors contributing to platinum drug resistance.

Discussion:

  • Investigates novel therapeutic strategies targeting cancer metastasis.
  • Examines the role of natural compounds like icariin (Epimedium) in glioblastoma invasion.
  • Highlights Naphtho[1,2-b]furan-4,5-dione from Avicennia marina for breast cancer metastasis.

Key Insights:

  • Discusses the PI3K inhibitor BEZ235 for colon cancer stem cells.
  • Covers the EZH1 inhibitor GSK343 in cervical cancer treatment.
  • Explores vitamin D3's potential in prostate cancer therapy.

Outlook:

  • Suggests a need for further research into these drug candidates and mechanisms.
  • Emphasizes the potential of natural products and targeted therapies in oncology.
  • Underscores the importance of understanding drug resistance for effective cancer treatment.
Keywords:
cancerdrug resistancemetastasis

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