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Updated: Mar 25, 2026
Fertility Preservation Through Oocyte Vitrification: Clinical and Laboratory Perspectives
Published on: September 16, 2021
Short versus long gonadotropin-releasing hormone analogue suppression protocols in advanced age women undergoing
Jianping Ou1, Weijie Xing1, Tao Li1
1a Center for Reproductive Medicine, The Third Affiliated Hospital of Sun Yat-Sen University , Guangzhou , China and.
Objective:
To compare the effective of two GnRH-a protocols for ovarian stimulation in advanced age women undergoing IVF/ICSI cycles.
Study Design:
A total of 1149 IVF-ET/ICSI cycles were retrospectively identified. The cycles were divided two groups, namely a long-protocol group and a short-protocol group.
Results:
The numbers of oocytes retrieved, and high-quality embryos in the long-protocol group were significantly greater than those in the short-protocol group. In the long-protocol group, the implantation and pregnancy rates were 17.22% and 33.67%, respectively, and these values were significantly higher than those in the short-protocol group (8.24% and 15.96%, p < 0.05).
Conclusions:
Our study demonstrated that the long protocol was superior to the short protocol for advanced age women.
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