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Related Experiment Video

Updated: Mar 25, 2026

Soft Lithographic Procedure for Producing Plastic Microfluidic Devices with View-ports Transparent to Visible and Infrared Light

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Published on: August 17, 2017

A simple approach for an optically transparent nanochannel device prototype.

Fupeng Liang¹, An Ju, Yi Qiao

¹State Key Laboratory of Bioelectronics, School of Biological Science and Medical Engineering, Southeast University, No.2 Si Pai Lou, Nanjing, 210096, China. zhlu@seu.edu.cn.

|February 20, 2016

Summary

This summary is machine-generated.

Researchers developed a fast, inexpensive method to create nanochannel devices using UV lasers and epoxy resin. This approach simplifies nanofluidics research by overcoming the high costs and complexity of traditional nanochannel fabrication.

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Last Updated: Mar 25, 2026

Soft Lithographic Procedure for Producing Plastic Microfluidic Devices with View-ports Transparent to Visible and Infrared Light

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Creating Sub-50 Nm Nanofluidic Junctions in PDMS Microfluidic Chip via Self-Assembly Process of Colloidal Particles

Creating Sub-50 Nm Nanofluidic Junctions in PDMS Microfluidic Chip via Self-Assembly Process of Colloidal Particles

Published on: March 13, 2016

Area of Science:

Materials Science
Nanotechnology
Chemical Engineering

Background:

Fabricating structure-controllable nanochannel devices is typically expensive and complex.
Existing methods often require specialized equipment and high-quality raw materials.
Faster, simpler, and more affordable nanochannel fabrication is needed to advance nanofluidics research.

Purpose of the Study:

To develop a cost-effective and straightforward method for fabricating nanochannel devices.
To enable rapid laboratory studies in the field of nanofluidics.
To create optically transparent nanochannels with controllable dimensions.

Main Methods:

Utilized a glass/epoxy resin/glass structure for device fabrication.
Engraved grooves on a glass substrate using a UV laser on an aluminum sacrificial layer.
Formed nanochannels by electrochemically etching sacrificial layers, with simultaneous fabrication of microfluidic inlets/outlets.

Main Results:

Achieved a simple and inexpensive nanochannel device fabrication process.
The total fabrication time was under 10 hours.
Successfully created optically transparent nanochannels with depths down to 20 nm.
Observed nanofluidic behaviors using optical and fluorescence microscopy.

Conclusions:

The developed method offers a fast, simple, and inexpensive approach to nanochannel fabrication.
This technique significantly reduces the barriers to entry for nanofluidics research.
The fabricated nanochannels are suitable for observing nanoscale fluid phenomena.