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Group-sequential three-arm noninferiority clinical trial designs

Toshimitsu Ochiai1,2, Toshimitsu Hamasaki2,3,4, Scott R Evans5

  • 1a Biostatistics Department , Shionogi & Co., Ltd. , Osaka , Japan.

Journal of Biopharmaceutical Statistics
|February 20, 2016
PubMed

Keywords:
Assay sensitivityCui-Hung-Wang statisticsType I erroraverage sample numberfixed margin approachfraction approachmaximum sample sizesample size recalculation

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