Siliconoma: Report of Two Cases
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Updated: Mar 25, 2026
Identification of OTX1 and OTX2 As Two Possible Molecular Markers for Sinonasal Carcinomas and Olfactory Neuroblastomas
Published on: February 28, 2019
Bruna Souza Felix Bravo1, Laila Klotz Almeida de Balassiano2, Julien Totti de Bastos3
1Instituto de Dermatologia Professor Rubem David Azulay da Santa Casa da Misericórdia do Rio de Janeiro (RJ) and Hospital Federal da Lagoa, Universidade Federal do Rio de Janeiro, Rua Dona Mariana 143, Botafogo, Rio De Janeiro, RJ, 22280-000, Brazil. brunabravo@globo.com.
Unlabelled:
Injectable silicone has been used illegally for more than 60 years. Siliconoma is the term used to describe a foreign body reaction in the human body caused by the presence of silicone. The aim of this study is to report two cases of patients who underwent application of large volumes of injectable silicone with non-medical and unqualified professionals, which led to serious complications sometime after the procedure.
Level Of Evidence V:
This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266.
