The relationship between left ventricular mass index and body composition in new-diagnosed hypertensive patients
1Department of Nephrology, Dr Abdurrahman Yurtaslan Oncology Training and Research Hospital, Ankara, Turkey.
Insights
Body fat percentage is linked to higher Left Ventricular Mass Index in new hypertension patients. Reducing body fat may lower Left Ventricular Hypertrophy risk, especially in obese individuals.
Area of Science:
- Cardiology
- Public Health
- Body Composition Analysis
Background:
- Cardiovascular disease (CVD) is a leading global cause of mortality.
- Hypertension and obesity are significant risk factors for CVD.
- Left Ventricular Mass Index (LVMI) is a key indicator of cardiac health.
Purpose of the Study:
- To investigate the association between body composition and LVMI in newly diagnosed hypertensive patients.
- To determine if body fat percentage is a predictor of LVMI in this population.
Main Methods:
- 120 newly diagnosed hypertensive patients were enrolled.
- Body fat percentage (BFP) measured using bioelectrical impedance analysis (BIA).
- Echocardiography used to assess LVMI.
Main Results:
- Females had higher body fat percentage, BMI, and LVMI than males.
- Patients with higher BFP (Group 3) showed increased BMI, inflammatory markers, and triglycerides.
- Higher BFP was independently associated with increased LVMI, along with age, weight, and gender.
Conclusions:
- Body fat percentage is significantly associated with higher LVMI in hypertensive patients.
- Assessing BFP can help identify individuals at higher risk for Left Ventricular Hypertrophy (LVH).
- Interventions targeting body fat reduction may be crucial for managing LVH in hypertensive and obese populations.
Background:
Cardiovascular disease (CVD) is considered a public health burden and most common cause of mortality in all over the world. The latency time for developing CVD may be several decades. the objective of this study was to examine the relationship between body composition and Left Ventriculare Mass Index (LVMI) in newly diognosed hypertensive patients.
Methods:
We enrolled 120 new-diagnosed hypertensive patients (mean age 45 ± 8 years) who admitted to our nephrology clinic. Body fat percentage (BFP) was measured by bioelectrical impedance (BIA). Echocardiography examinations were performed for all patients.
Results:
Mean values of Waist hip ratio, Body mass ındex, Body fat percentage, Systolic blood pressure, Diastolic blood pressure were significantly higher for females than males (all p values <0.05). The female patients had higher LVMI than male patients (94.8 ± 13.1 vs 89.2 ± 14.6, p < 0.05). The study patients were divided into 3 groups according to their BFP defined by BIA. Group 3 patients, who exhibited higher body fat, had significantly higher BMI (p < 0,05), total leukocyte count (p < 0.05), CRP (p < 0.05), triglyceride (p < 0.05), and female predominance. Group 3 patients were statistically older than group 1 patients (46.2 vs. 40.6 years, p < 0.05). Additionally, LVMI levels were higher in Group 3 than Group 1 (p < 0.05) (Table 3). In logistic regression analysis, independent factors affecting LVMI were age, weight, gender and BFP (all p values were <0.05).
Conclusions:
BFP was associated with higher LVMI, in newly diognosed hypertensive patients. Its use results in significantly lower proportions of individuals with LVH in the population, in particular among hypertensive and the obese patients.
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