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Published on: May 24, 2021
Right Ventricular Imaging in 25 Seconds: Evaluating the Use of Sparse Sampling CINE With Iterative Reconstruction for
Holger Haubenreisser1, Thomas Henzler, Johannes Budjan
1From the *Institute of Clinical Radiology and Nuclear Medicine, University Medical Center Mannheim, Medical Faculty Mannheim, Heidelberg University; †DZHK (German Centre for Cardiovascular Research) Partner Site, Mannheim; ‡MR Product Innovation and Definition, Healthcare Sector, Siemens AG, Erlangen, Germany; §Imaging and Computer Vision, Siemens AG, Corporate Technology, Princeton, NJ; and ∥First Department of Medicine, University Medical Center Mannheim, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.
Objective:
The aim of this study was to prospectively evaluate a 2-dimensional real-time CINE TrueFISP magnetic resonance sequence using sparse data sampling with iterative reconstruction (SSIR) for right ventricular (RV) volumetry in comparison to the criterion standard (CS) acquired at 3 T.
Materials And Methods:
Ten healthy controls and 20 consecutive patients scheduled for cardiac magnetic resonance imaging on a 3-T system (Magnetom Skyra; Siemens Healthcare Sector, Germany) underwent undersampled SSIR sequences with a single breath-hold (BH) as well as with shallow free breathing (NBH) and a fully sampled multi-BH sequence as CS. Right ventricular volumetry was performed with dedicated cardiac magnetic resonance software (cvi42; Circle Cardiovascular Imaging Inc, Calgary, Alberta, Canada). Agreement of SSIR with and without BH and CS for RV functional parameters (end-systolic volume [RVESV], end-diastolic volume [RVEDV], stroke volume [RVSV], and ejection fraction [RVEF]) were assessed with Bland-Altman analysis and paired t test.
Results:
Analysis of the 30 individuals (19 male; 48 ± 14 years) revealed no significant differences when comparing CS and BH measurements for RVEDV (153.7 vs 153.6 mL, P = 0.96), RVESV (71.6 vs 72.1 mL, P = 0.78), RVSV (82.0 vs 81.6 mL, P = 0.65), and RVEF (54.9% vs 54.2%, P = 0.19). Similar results were shown when comparing CS and NBH measurements for RVEDV (153.7 vs 152.2 mL, P = 0.34), RVESV (71.6 vs 72.8 mL, P = 0.30), RVSV (82.0 vs 81.0 mL, P = 0.46), and RVEF (54.9 vs 54.4, P = 0.48). Time taken for acquisition was 350 seconds for the CS, 34 seconds for BH, and 25 seconds for NBH measurements. Additional time required for iterative reconstruction was 2 minutes and 30 seconds for the sparse sampled data sets.
Conclusions:
Our results demonstrate that accurate RV volumetry with SSIR data at 3 T is feasible in clinical routine within 25 seconds even without BH, which is of particular importance in patients with dyspnea.
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