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Updated: Mar 25, 2026

08:34
Proton Therapy Delivery and Its Clinical Application in Select Solid Tumor Malignancies
Published on: February 6, 2019
21.3K
[Localized prostate cancer: Radiotherapeutic concepts]
1Klinik für Strahlentherapie und Radioonkologie, Universitätsmedizin Mannheim, Theodor-Kutzer-Ufer 1-3, 68135, Mannheim, Deutschland. mario.grimm@umm.de.
Der Urologe. Ausg. A
|February 20, 2016
Summary
Radiation therapy is a key prostate cancer treatment. Advances like IMRT and IGRT improve precision, reduce side effects, and allow higher doses, offering better outcomes.
Area of Science:
- Oncology
- Radiation Oncology
- Urologic Oncology
Background:
- Radiation therapy is a foundational treatment for prostate cancer.
- Recent decades have seen significant advancements in radiation therapy techniques and concepts.
Purpose of the Study:
- To provide a comprehensive overview of current prostate cancer radiation therapy standards of care.
- To discuss recent technical and conceptual developments in the field.
Main Methods:
- Review of established and emerging radiation therapy modalities for prostate cancer.
- Analysis of treatment precision, side effect profiles, and dose escalation capabilities.
Main Results:
- Three-dimensional conformal radiotherapy remains a standard for percutaneous radiotherapy.
- Intensity-modulated radiation therapy (IMRT) and image-guided radiation therapy (IGRT) enhance treatment precision, minimize side effects, and enable dose escalation.
- Low dose rate (LDR) and high dose rate (HDR) brachytherapy are viable options for localized prostate cancer, offering a distinct side effect profile.
Conclusions:
- IMRT and IGRT represent significant improvements over traditional radiotherapy for prostate cancer.
- Brachytherapy provides an alternative treatment option with specific benefits and side effects.
- Further investigation in prospective trials is needed for proton therapy and stereotactic radiotherapy in prostate cancer treatment.
Keywords:
BrachytherapyProstate cancerRadiotherapy, external-beamRadiotherapy, image-guidedRadiotherapy, intensity-modulated
