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Updated: Mar 25, 2026

A Free-breathing fMRI Method to Study Human Olfactory Function
Published on: July 30, 2017
Improved low-cost, MR-compatible olfactometer to deliver tobacco smoke odor
Steven B Lowen1, Stacey L Farmer2, Scott E Lukas2
1McLean Imaging Center, McLean Hospital/Harvard Medical School, 115 Mill Street, Belmont, MA, 02478, USA. lowen@mclean.harvard.edu.
Abstract:
We describe a low-cost, MRI-compatible olfactometer that delivers fresh cigarette smoke odor, a challenging odorant to present, as well as other odorants. This new olfactometer retains all of the advantages of an earlier design that was capable of only delivering volatile odors (Lowen & Lukas, Behavior Research Methods, 38, 307-313, 2006). The new system incorporates a novel switching mechanism that allows it to deliver fresh smoke generated from a burning cigarette during a stimulus presentation paradigm that might be employed in a cue-reactivity experiment. An evaluation study established that the olfactometer reliably delivered smoke to the participants and that tobacco smoke was discriminated from other odorants; there were no adverse reactions to the device.
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