The Effect of Changing Scan Mode on Trabecular Bone Score Using Lunar Prodigy

Area of Science:

• Osteoporosis Research
• Medical Imaging Analysis
• Bone Densitometry

Background:

• Trabecular bone score (TBS) assesses bone microarchitecture and predicts fracture risk.
• TBS is increasingly used in osteoporosis assessment and integrated into FRAX®.
• GE Lunar DXA machines utilize different acquisition modes (thin, standard, thick) based on patient anatomy.

Purpose of the Study:

• To investigate the impact of different acquisition modes on TBS values.
• To compare TBS measurements from standard and thick modes on the GE Lunar Prodigy.
• To determine if scanning mode affects TBS in osteoporosis assessment.

Main Methods:

• Retrospective review of 30 patients with paired lumbar spine DXA scans (standard and thick modes).
• Scans performed on GE Lunar Prodigy on the same day without repositioning.
• Analysis of lumbar spine bone mineral density (L1-L4) and TBS from paired scans.

Main Results:

• No significant difference in lumbar spine bone mineral density between standard and thick modes.
• Significantly higher TBS values were observed in thick mode compared to standard mode (mean difference: 0.24, 20%).
• TBS values demonstrated a statistically significant difference based on the acquisition mode used.

Conclusions:

• Preliminary data indicate that TBS values from GE Lunar Prodigy are dependent on the scanning acquisition mode.
• Further research is needed to understand the cause of this discrepancy.
• Development of appropriate protocols is required to ensure consistent TBS measurements across different scanning modes.