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Updated: Mar 25, 2026

3-D Imaging and Analysis of Neurons Infected In Vivo with Toxoplasma gondii
Published on: December 9, 2014
Acquired Toxoplasmosis Presenting with a Brainstem Granuloma in an Immunocompetent Adolescent
Nitin Manwani1, K Ravikumar, V Viswanathan
1Departments of Pediatric Intensive Care, Pediatric Neurology, *Pediatric Neurosurgery, Kanchi Kamakoti CHILDS Trust Hospital and CHILDS Trust Medical Research Foundation (CTMRF), Chennai; and Department of Neuropathology, National Institute of Mental Health and Neuro Sciences (NIMHANS), Bangalore, India. Correspondence to: Dr Nitin Manwani, Department of Pediatric Intensive Care, Kanchi Kamakoti CHILDS Trust Hospital, 12A, Nageswara Road, Nungambakkam, Chennai 600 034, India. drnitin171@gmail.com.
Background:
Toxoplasmosis is an uncommon disease in immunocompetent people.
Case Characteristics:
We report an adolescent boy with central nervous system toxoplasmosis who presented with progressive lower cranial nerve palsies and a ring-enhancing lesion on neuroimaging.
Intervention:
Diagnosis of toxoplasmosis was confirmed on histopathology of the excised lesion.
Message:
Toxoplasmosis should be considered in the differential diagnosis of focal brain lesions irrespective of immune status.
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