Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Video

Updated: Mar 25, 2026

CD4+ T-Lymphocyte Capture Using a Disposable Microfluidic Chip for HIV
12:44

CD4+ T-Lymphocyte Capture Using a Disposable Microfluidic Chip for HIV

Published on: October 1, 2007

8.1K

Microfluidic devices with templated regular macroporous structures for HIV viral capture.

Krissada Surawathanawises1, Kathryn Kundrod2, Xuanhong Cheng3

  • 1Department of Materials Science and Engineering, Lehigh University, Bethlehem, PA 18015, USA.

The Analyst
|February 23, 2016
PubMed
Summary

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

3D-Printed SiO<sub>2</sub>-BaTiO<sub>3</sub>/SrTiO<sub>3</sub>‑Polymeric Composites for Enhanced Photocatalytic and Piezocatalytic Mitigation of Methylene Blue and Tetracycline Pollutants.

ACS omega·2026
Same author

MICROWAVE BIOSENSORS for SINGLE-CELL DIELECTRIC CHARACTERIZATION: a REVIEW.

IEEE microwave magazine·2026
Same author

Effect of Pulse Frequency on Shear-Induced Extension of Von Willebrand Factor in Continuous-Flow Ventricular Assist Device (CF-VAD).

ASAIO journal (American Society for Artificial Internal Organs : 1992)·2025
Same author

Water Harvesting Performance of Modified Nanostructure Aluminum Using Silica Nanoparticles Coating and Laser Processing.

Nanomaterials (Basel, Switzerland)·2025
Same author

Understanding the role of vascular stretch on modulation of VWF and ANGPT-2 in continuous flow left ventricular assist device (CF-VAD) patients.

Lab on a chip·2025
Same author

Aptamer-based biotherapeutic conjugate for shear responsive release of Von Willebrand factor A1 domain.

Nanoscale·2024

Researchers developed novel microfluidic devices using macroporous materials for efficient viral sample processing. These inexpensive, portable devices achieved high capture efficiencies for human immunodeficiency virus (HIV), offering a promising solution for resource-limited settings.

Area of Science:

  • Biomedical Engineering
  • Nanotechnology
  • Virology

Background:

  • Resource-limited settings require cost-effective, portable solutions for viral sample processing.
  • Current methods for virus capture often lack efficiency and accessibility.

Purpose of the Study:

  • To develop and evaluate microfluidic devices with macroporous materials for efficient virus capture.
  • To address the need for simple, portable viral diagnostic tools in resource-limited environments.

Main Methods:

  • Incorporation of macroporous materials with regular nanostructures (nanopost array, spherical pore network) into microfluidic devices.
  • Fabrication of porous structures using templating methods (anodic aluminum oxide films, silica particles).
  • Testing microdevices for human immunodeficiency virus (HIV) isolation using affinity chromatography.

More Related Videos

Single-Cell Characterization of Calcium Influx and HIV-1 Infection using a Multiparameter Optofluidic Platform
07:15

Single-Cell Characterization of Calcium Influx and HIV-1 Infection using a Multiparameter Optofluidic Platform

Published on: May 18, 2021

3.6K
Cell Capture Using a Microfluidic Device
29:02

Cell Capture Using a Microfluidic Device

Published on: October 1, 2007

5.8K

Related Experiment Videos

Last Updated: Mar 25, 2026

CD4+ T-Lymphocyte Capture Using a Disposable Microfluidic Chip for HIV
12:44

CD4+ T-Lymphocyte Capture Using a Disposable Microfluidic Chip for HIV

Published on: October 1, 2007

8.1K
Single-Cell Characterization of Calcium Influx and HIV-1 Infection using a Multiparameter Optofluidic Platform
07:15

Single-Cell Characterization of Calcium Influx and HIV-1 Infection using a Multiparameter Optofluidic Platform

Published on: May 18, 2021

3.6K
Cell Capture Using a Microfluidic Device
29:02

Cell Capture Using a Microfluidic Device

Published on: October 1, 2007

5.8K

Main Results:

  • Achieved 80-99% capture efficiency for HIV particles using functionalized porous microdevices under continuous flow.
  • Demonstrated significantly higher capture efficiency compared to functionalized flatbed microchannels (around 10%).
  • Nanostructure dimensions are tunable, allowing adaptation for capturing various submicron bioparticles.

Conclusions:

  • The developed microfluidic devices offer high efficiency and ease of operation for viral capture.
  • These devices are suitable for resource-limited settings and potential point-of-care diagnostics.
  • The technology can be adapted for capturing diverse submicron bioparticles, broadening its application scope.