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Updated: Mar 25, 2026

A Reproducible Intensive Care Unit-Oriented Endotoxin Model in Rats
Published on: February 20, 2021
Point prevalence of general ward patients fulfilling criteria for systemic inflammatory response syndrome
L Douglas1, A Casamento1, D Jones1,2
1Department of Intensive Care, Austin Hospital, Melbourne, Victoria, Australia.
Abstract:
The systemic inflammatory response syndrome (SIRS) is defined by abnormal temperature, heart rate, minute ventilation or white cell count and can be due to infectious or non-infectious causes. In a single day, 23% of hospital ward patients fulfilled SIRS criteria. Patients with SIRS were more likely to be under medical than surgical units. One-third of the patients had evidence of infection. There was no association between SIRS criteria and increased mortality or hospital length of stay.
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