Determinants of failure to thrive (FTT) among infants aged 6-24 months: a case-control study

H Habibzadeh1, H Jafarizadeh2, A Didarloo3

  • 1School of Nursing and Midwifery, Urmia University of Medical Sciences, Serow Highway, Nazlou, Urmia, Iran;

Insights

Maternal education, breastfeeding duration, birth weight, and family income are key risk factors for failure to thrive (FTT) in infants. Birth order can be a protective factor, guiding interventions for child growth.

Area of Science:

  • Pediatrics
  • Public Health
  • Nutrition Science

Background:

  • Failure to thrive (FTT) poses a significant global health challenge, particularly in developing regions.
  • Untreated FTT can lead to severe, long-term health consequences for children.
  • Identifying risk factors is crucial for effective FTT prevention and management.

Purpose of the Study:

  • To investigate the specific risk factors associated with FTT in infants under two years of age.
  • To provide data from Urmia, Northwest Iran, to inform local and broader public health strategies.
  • To identify modifiable factors for targeted interventions.

Main Methods:

  • A case-control study involving 445 infants (180 cases, 265 controls) aged 6-24 months.
  • Data collected via questionnaires on sociodemographic, infant demographic, and nutrition-related variables.
  • Statistical analysis included chi-square tests and logistic regression to determine risk factor significance.

Main Results:

  • Maternal education level, breastfeeding duration, infant birth weight, and family monthly income were identified as significant risk factors for FTT.
  • Higher maternal education, longer breastfeeding, higher birth weight, and increased family income correlated with reduced FTT risk.
  • Infant birth order was found to be a protective factor against FTT.

Conclusions:

  • Study findings offer valuable insights for healthcare providers to develop targeted interventions for FTT.
  • Educating mothers and caretakers on nutrition and growth is essential for preventing FTT and associated health issues.
  • Addressing socioeconomic and nutritional determinants can significantly improve infant health outcomes.
Abstract

Related Concept Videos

Nature and Nurture01:10

Nature and Nurture

Many human characteristics, like height, are shaped by both nature—in other words, by our genes—and by nurture, or our environment. For example, chronic stress during childhood inhibits the production of growth hormones and consequently reduces bone growth and height. Scientists estimate that 70-90% of variation in height is due to genetic differences among individuals, and 10-30% of variation in height is due to differences in the environments that individuals experience,...
22.8K
Attachment01:20

Attachment

Attachment is vital for infant development, as warm social interactions support growth and well-being. In a classic 1958 study by Harry Harlow, the significance of warmth and comfort in forming attachments was examined. Harlow separated newborn monkeys from their mothers and provided two artificial "mothers": one made of cold wire and the other covered in soft cloth. Despite the wire mother offering food, the infant monkeys preferred the comfort of the cloth mother, demonstrating that...
700
Development of Human Microbiota01:30

Development of Human Microbiota

The human microbiota begins developing at birth and undergoes continual change as we age. Infancy marks a critical period of microbial sensitivity, offering a “window of opportunity” during which beneficial microbes help mature the immune system. By age three, children typically develop a more stable and diverse microbial community. Newborns acquire microbes from their immediate environment; vaginal delivery favors maternal vaginal microbes, while cesarean births favor microbes from...
15
Socioemotional Development during Infancy01:30

Socioemotional Development during Infancy

Socio-emotional development in infancy is primarily shaped by early emotional responses and social connections, with temperament playing a central role. Temperament refers to the consistent patterns in an individual's emotional and behavioral responses, observable even in infancy. By examining temperament, researchers can better understand an infant's unique ways of interacting with the world, influencing subsequent personality and socio-emotional growth.
Primary Temperament Types
1.2K
Development of the Oral Microbiota01:28

Development of the Oral Microbiota

The establishment of the oral microbiome begins before birth, challenging the long-held belief that the fetal oral cavity is sterile. The presence of oral microbes such as Streptococcus and Fusobacterium in amniotic fluid suggests that microbial exposure may occur in utero, potentially through translocation from the maternal oral or gastrointestinal tract. This early colonization primes the neonatal immune system and sets the stage for subsequent microbial succession. Maternal health,...
19
Relationship with Parents: Attachment01:28

Relationship with Parents: Attachment

Parent-child interactions lay the foundation for how we understand relationships throughout life. These interactions are not uniform across families; instead, they are shaped by a range of environmental, emotional, and behavioral factors unique to each caregiver-child dynamic. Social psychologists study these early relationships to understand how patterns formed in infancy influence social functioning and interpersonal behavior in adulthood.Attachment Theory and Early Relational ModelsJohn...
339