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Updated: Mar 25, 2026

Cultivating a Three-dimensional Reconstructed Human Epidermis at a Large Scale
Published on: May 28, 2021
[Structure, function and reconstruction of skin surface lipid film]
Benrong Lu1, Yi Liu, Shilong Li
1Center of Burns and Plastic Surgery of PLA, Lanzhou General Hospital of Lanzhou Military Command, Lanzhou 730050, China.
Abstract:
After healing of burn wound, skin of scar, transplanted skin grafts, and healed donor site wound suffer from temporary or permanent loss of function of sebaceous glands and dysfunction of skin surface lipid film formation, resulting in desiccation, desquamation, and sensitiveness of the skin, making areas of newly formed skin unsatisfactory. Therefore a good rehabilitation may fail. In this paper, the composition, physiochemical properties, and reconstruction of skin surface lipid film are discussed.
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